WASHINGTON, D.C. 20549

                                   FORM 12B-25

                           NOTIFICATION OF LATE FILING

[ ] Form 1O-K  [ ] Form 20-F  [ ] Form 11-K  [X] Form 10-Q  [ ] Form N-SAR

For Period Ended:  September 30, 2004

[ ]     Transition Report on Form 10-K
[ ]     Transition Report on Form 20-F
[ ]     Transition Report on Form 11-K
[ ]     Transition Report on Form 10-Q
[ ]     Transition Report on Form N-SAR
For the Transition Period Ended:

         Read Attached Instruction Sheet Before Preparing Form. Please Print or

         Nothing in this form shall be construed to imply that the Commission
         has verified any information contained herein.

         If the notification relates to a portion of the filing checked above,
         identify the Item(s) to which the notification relates:


         Full Name of Registrant: BioSpecifics Technologies Corp.

         Former Name if Applicable: N/A

         Address of Principal Executive Office (Street and Number):
         35 Wilbur Street

         City, State and Zip Code: Lynbrook, New York 11563


If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b) [Paragraph 23,047],
the following should be completed. (Check box, if appropriate)

[x]     (a) The reasons described in reasonable detail in Part III of this form
could not be eliminated without unreasonable effort or expense;

[x]     (b) The subject annual report, semi-annual report, transition report on
Form 10-K, Form 20-F, 11-K or Form N-SAR, or portion thereof will be filed on or
before the fifteenth calendar day following the prescribed due date; or the
subject quarterly report or transition report on Form 10-Q, or portion thereof
will be filed on or before the fifth calendar day following the prescribed due
date; and [Amended in Release No. 34-26589 (Paragraph 72,435), effective April
12, 1989, 54 F.R. 10306.]

[ ] (c) The accountant's statement or other exhibit required by Rule 12b-25(c)
has been attached if applicable.


State below in reasonable detail the reasons why the Form 1O-K, 20-F, 11-K,
10-Q, N-SAR, or the transition report or portion thereof could not be filed
within the prescribed time period. [Amended in Release No. 34-26589
(Paragraph 72,435), effective April 12, 1989, 54 F.R. 10306.]

The Company's Quarterly Report on Form 10-QSB will not be filed within the
prescribed time due to unexpected delay in preparation of the 10QSB.


         (1) Name and telephone number of person to contact in regard to this

         Thomas Wegman                  516               593-7000
         -------------                  ---               --------
         (Name)                     (Area Code)      (Telephone Number)

         (2) Have all other periodic reports required under Section 13 or 15(d)
of the Securities Exchange Act of 1934 or Section 30 of the Investment Company
Act of 1940 during the preceding 12 months or for such shorter period that the
registrant was required to file such report(s) been filed? If the answer is no,
identify report(s).

                      [ ] Yes                [X] No

10-KSB 12/03, 10-QSB 3/04, 10-QSB 6/04

         (3) Is it anticipated that any significant change in results of
operations from the corresponding period for the last fiscal year will be
reflected by the earnings statements to be included in the subject report or
portion thereof?

                      [ ] Yes                [X] No

         If so: attach an explanation of the anticipated change, both
narratively and quantitatively, and, if appropriate, state the reasons why a
reasonable estimate of the results cannot be made. (See attachment).

                         BioSpecifcs Technologies Corp.
                  (Name of Registrant as specified in charter)

has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.

Date:  November 12, 2004                        By:  Thomas Wegman
                                                Name: Thomas Wegman
                                                Title: Executive Vice President