Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  PRUDENTIAL FINANCIAL INC
 2. Date of Event Requiring Statement (Month/Day/Year)
11/16/2018		 3. Issuer Name and Ticker or Trading Symbol
ClearBridge Energy Midstream Opportunity Fund Inc. [EMO]
(Last)
(First)
(Middle)
751 BROAD ST		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEWARK, NJ 07102		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Series F Mandatory Redeemable Preferred Stock 41 (1)
I
By The Prudential Insurance Company of America, a wholly-owned subsidiary of the Reporting Person
Series G Mandatory Redeemable Preferred Stock 24 (1)
I (2)
By The Prudential Insurance Company of America, a wholly-owned subsidiary of the Reporting Person
Series G Mandatory Redeemable Preferred Stock 85 (1)
I (3)
By Prudential Legacy Insurance Company of New Jersey, a wholly-owned subsidiary of the Reporting Per

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
PRUDENTIAL FINANCIAL INC
751 BROAD ST
NEWARK, NJ 07102		     X    
PRUDENTIAL LEGACY INSURANCE CO OF NEW JERSEY
751 BROAD STREET
NEWARK, NJ 07102		     X    

Signatures

Prudential Financial, Inc. By:/s/Hillary Lorenzo, Vice President 11/21/2018
**Signature of Reporting Person Date
Prudential Legacy Insurance Company of New Jersey By: PGIM, Inc., as Investment Manager By:/s/Christopher Halloran, Vice President 11/21/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) (1)Share exchange/replacement by EMO due to ClearBridge American Energy MLP Fund Inc. (ticker: CBA)'s merger into EMO on 11/16/2018.
(2) (2)As grantor of the PICA Hartford Life & Annuity Comfort Trust.
(3) (3)Preferred stock owned directly by Prudential Legacy Insurance Company of New Jersey, a ten percent owner of a class, and indirectly owned by Prudential Financial, Inc., its parent holding company.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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