Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Ares Trading S.A.
 2. Date of Event Requiring Statement (Month/Day/Year)
12/28/2018		 3. Issuer Name and Ticker or Trading Symbol
INTREXON CORP [XON]
(Last)
(First)
(Middle)
ZONE INDUSTRIELLE DE L'OURIETTAZ		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

AUBONNE, V8 1170		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock (1) 20,640,119
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Ares Trading S.A.
ZONE INDUSTRIELLE DE L'OURIETTAZ
AUBONNE, V8 1170		     X    
Merck KGaA
FRANKFURTER STRASSE 250
DARMSTADT, 2M 64293		     X    
MERCK SERONO S.A.
ZONE INDUSTRIELLE
COINSINS, V8 1267		     X    

Signatures

/s/ Cedric Hyde 01/22/2019
**Signature of Reporting Person Date
/s/ Luigia Bocola 01/22/2019
**Signature of Reporting Person Date
/s/ Rando Bruns 01/22/2019
**Signature of Reporting Person Date
/s/ Tim Nielsen 01/22/2019
**Signature of Reporting Person Date
/s/ Cedric Hyde 01/22/2019
**Signature of Reporting Person Date
/s/ Tearaboth Te 01/22/2019
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) In addition to the securities reported herein, Ares Trading S.A. holds a Convertible Note in the original principal amount of $25,000,000 which is convertible at any time into Common Stock of the Issuer, subject to limited exceptions, at a conversion price equal to (a) the volume weighted-average price per share of the Common Stock on the Nasdaq Stock Market for the consecutive ten trading days immediately prior to the conversion date as reported by Bloomberg, L.P. or (b) if converted in connection with a qualified public offering by the Issuer, the lowest price per share paid by a purchaser in such qualified public offering. The Convertible Note and shares of Issuer Common Stock issuable thereunder, which are not reported as beneficially owned herein pursuant to Rule 16a-1(c)(6) promulgated under the Securities Exchange Act of 1934, are more fully described in the Schedule 13G filed by the Reporting Persons on January 7, 2019.
 
Remarks:
This Form 3 is being filed by each of the following persons (together, the Reporting Persons): Ares Trading SA, the direct beneficial owner of the shares, Merck Serono SA, Coinsins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany, an indirect beneficial owner of the shares, and Merck KGaA, Darmstadt, Germany, an indirect beneficial owner of the shares. The Reporting Persons have entered into a joint filing agreement (Exhibit 99). Ares Trading SA is a dominantly controlled subsidiary of Merck Serono SA, Coinsins, Switzerland, an affiliate of Merck KGaA, Darmstadt, Germany. Merck Serono SA, Coinsins, Switzerland is a wholly owned indirect subsidiary of Merck KGaA, Darmstadt, Germany. Merck KGaA, Darmstadt, Germany is a publicly traded company (Frankfurt Stock Exchange, DAX 30) and the beneficiary of the two companies.

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