Aradigm Corporation Prospectus Supplement #2
 

     
Prospectus Supplement No. 2
(To Prospectus dated April 15, 2003)
  Filed Pursuant to Rule 424(b)(3) and (c)
SEC File No. 333-104119

(ARADIGM CORPORATION LOGO)

27,281,687 Shares
Common Stock

     This is a supplement to the prospectus, dated April 15, 2003 forming a part of the Registration Statement on Form S-3 (Registration No. 333-104119) filed by Aradigm Corporation relating to the offering and sale by selling stockholders of Aradigm (or by donees, pledgees, transferees and other successors in interest that receive such shares as a gift, pledge, partnership distribution or other non-sale transfer) of up to 27,281,687 shares of our common stock, which includes 4,016,124 shares of common stock issuable to the selling stockholders upon the exercise of warrants to purchase common stock. This prospectus supplement should be read in conjunction with the prospectus, and this prospectus supplement is qualified by reference to the prospectus, except to the extent that the information provided by this prospectus supplement supersedes the information contained in the prospectus.

     The purpose of this prospectus supplement is to supplement the information set forth in the Prospectus regarding the selling security holders and to replace the selling security holder table set forth in the Prospectus Supplement No. 1 filed with the Securities and Exchange Commission on June 9, 2003. The table below includes (1) a correction to the footnote set forth in the prospectus for Penn Footwear Co., (2) the change in the holdings for New Enterprise Associates 10, Limited Partnership to reflect the distribution of an aggregate of 4,000,000 additional shares of our common stock to its partners and (3) for the selling security holders who received shares from New Enterprise Associates in this distribution:

    their name
 
    the shares of common stock beneficially owned as of June 17, 2003
 
    the shares of our common stock offered under the Prospectus
 
    the shares of our common stock owned after the offering

     All of the information regarding beneficial ownership was furnished to us by or on behalf of the selling security holders. Beneficial ownership of the common stock listed in the table has been determined in accordance with the applicable rules and regulations under the Exchange Act of 1934.

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Penn Footwear Co. (3)
    930,378       1.6 %     930,378             --  
New Enterprise Associates 10, Limited Partnership (4)
    9,080,373       14.7       2,198,605       6,881,768       11.2 %
NEA Partners 10, Limited Partnership
    70,027       *       70,027              
California State Teachers Retirement System
    344,393       *       344,393              
Washington State Investment Board
    331,478       *       331,478              
BSNEA I, L.L.C
    301,343       *       301,343              
California Emerging Ventures II, LLC
    226,007       *       226,007              
Procific
    150,672       *       150,672              
Commonwealth of Pennsylvania State Employees’ Retirement System
    105,471       *       105,471              
J.P. Morgan Pooled Venture Capital Institutional Investors II LLP
    105,408       *       105,408              
Boston Safe Deposit and Trust, not individually but solely in its capacity as trustee of the Lucent Technologies Inc. Master Pension Trust
    103,318       *       103,318              
HarbourVest Partners VI-Partnership Fund L.P.
    95,569       *       95,569              
The Chase Manhattan Bank, as Trustee for First Plaza Group Trust
    86,098       *       86,098              
Top Tier Investments, LLC
    86,098       *       86,098              
Deutsche Banc Alex Brown Venture Investors Portfolio, LLC
    75,336       *       75,336              
Danske Private Equity Partners K/S by Danske Private Equity A/S, its general partner
    68,879       *       68,879              
Crossroads Constitution Limited Partnership
    60,269       *       60,269              
Mellon Bank, N.A., as Trustee for the Bell Atlantic Master Trust
    60,268       *       60,268              
CDB Web Tech International LP
    60,268       *       60,268              
Asset Management Private Equity, L.P.
    60,268       *       60,268              
The Norinchukin Bank
    60,268       *       60,268              
State Teachers Retirement System of Ohio
    60,268       *       60,268              
Salomon Smith Barney Venture Opportunities Fund III, L.P.
    60,268       *       60,268              
Pension Reserves Investment Management Board
    51,659       *       51,659              
Virginia Retirement System
    51,659       *       51,659              
Citigroup Employee Fund of Funds I, L.P.
    45,290       *       45,290              
Partners Group Private Equity Performance Holding Limited
    45,201       *       45,201              
Private Equity Technology Partners III, C.V.
    45,201       *       45,201              
Saratoga Investments, LP
    45,201       *       45,201              
University Technology Ventures, L.P.
    45,201       *       45,201              
Old Westbury Venture Capital Fund II, LLC
    39,349       *       39,349              
Fort Washington Private Equity Investors III, L.P.
    34,439       *       34,439              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Barr Foundation
    34,439       *       34,439              
Mellon Bank, N.A., solely in its capacity as Trustee for the Bayer Corporation Master Trust, (as directed by Bayer Corporation), and not in its individual capacity
    34,439       *       34,439              
Northwestern University
    34,439       *       34,439              
Wilshire U.S. Private Markets Fund IV, L.P. (A)
    34,439       *       34,439              
Pine Street I Holdings LLC
    31,325       *       31,325              
DLJ Private Equity Partners Fund II, L.P.
    31,124       *       31,124              
The New Mexico State Investment Council Land Grant Permanent Fund
    30,285       *       30,285              
BSNEA II, L.L.C
    30,135       *       30,135              
BSNEA IV, L.L.C
    30,135       *       30,135              
Catherine M. Conover
    30,135       *       30,135              
Castle Private Equity (International) plc
    30,135       *       30,135              
Bankers Trust as a Trustee for an Undisclosed Limited Partner
    30,135       *       30,135              
Robert and Ruth Halperin Foundation
    30,135       *       30,135              
Lansforsakringar Liv Forsakringsaktiebolag (publ)
    30,135       *       30,135              
LGT Capital Invest Limited
    30,135       *       30,135              
Pearl Holding Limited
    30,135       *       30,135              
Private Equity Investor PLC
    30,135       *       30,135              
Private Equity Portfolio Fund III, LLC
    30,135       *       30,135              
U.A. Local 467 Pension Trust Fund
    30,135       *       30,135              
BancBoston Investments Inc.
    26,518       *       26,518              
J.P. Morgan Pooled Venture Capital Private Investors II LLC
    26,467       *       26,467              
DAF Global, LLC
    26,135       *       26,135              
Fairview Ventures Fund I, L.P.
    25,829       *       25,829              
Meyer Memorial Trust
    24,108       *       24,108              
BSC Venture Fund LLC
    20,919       *       20,919              
Abbott Capital Private Equity Fund III, L.P., by Abbott Capital Management, LLC, its Investment Manager
    20,664       *       20,664              
Commonfund Capital Venture Partners VI, L.P.
    20,664       *       20,664              
Thomas Weisel Global Growth Partners (B), L.P.
    19,549       *       19,549              
Pomona Partnership Holdings III Portfolio, LP
    17,683       *       17,683              
Alaska State Pension Investment Board by Abbott Capital Management, LLC, its Investment Manager
    17,220       *       17,220              
Tucker Anthony Private Equity Fund IV L.P.
    17,220       *       17,220              
Cornell University
    17,220       *       17,220              
Credit Suisse First Boston Guernsey Branch
    17,220       *       17,220              
Alfred I. DuPont Trust
    17,220       *       17,220              
The Ford Foundation
    17,220       *       17,220              
Iowa Public Employees’ Retirement System
    17,220       *       17,220              
The Mohawk River Fund II L.P.
    17,220       *       17,220              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Montagu Newhall Global Equity Partners LP
    17,220       *       17,220              
Pensioenfonds Metaal en Techniek
    17,220       *       17,220              
Kleinwort Benson (Channel Islands) Limited as Custodian for Preferential II Limited
    17,220       *       17,220              
Barings (Ireland) Limited as Custodian for Schroder Private Equity Funds plc
    17,220       *       17,220              
SVB Strategic Investors Fund, L.P.
    17,220       *       17,220              
U.S. Bancorp Piper Jaffray Private Equity Partners I, L.P.
    17,220       *       17,220              
Utah Retirement Systems, by Abbott Capital Management, LLC, its Investment Manager
    17,220       *       17,220              
The Rector & Visitors of the University of Virginia (A)
    17,220       *       17,220              
BSNEA III, L.L.C
    19,067       *       15,067       4,000       *  
Georgia Tech Foundation, Inc.
    15,067       *       15,067              
Rockefeller Brothers Fund, Inc.
    15,067       *       15,067              
Rockefeller Foundation
    15,067       *       15,067              
Southwestern Medical Foundation
    15,067       *       15,067              
3Com Ventures, Inc.
    15,067       *       15,067              
Citigroup Pension Plan
    15,067       *       15,067              
Crown Premium Private Equity Technology Ventures SICAV
    15,067       *       15,067              
W.K. Kellogg Foundation Trust
    15,067       *       15,067              
John S. and James L. Knight Foundation
    15,067       *       15,067              
Boston Safe Deposit and Trust Company, solely in its capacity as Trustee of The Kroger Co. Master Retirement Trust, (as directed by The Kroger Co.), and not in its individual capacity
    15,067       *       15,067              
MSD Portfolio LP — Investments
    15,067       *       15,067              
myCFO Investment Partners I, L.P.
    15,067       *       15,067              
Nider Investments, LLC
    15,067       *       15,067              
Oberlin College
    15,067       *       15,067              
QP Investments LLC
    15,067       *       15,067              
RMF Private Equity Fund 2001, L.P.
    15,067       *       15,067              
Professor Richard Sapper
    15,067       *       15,067              
Vega Invest (Guernsey), Limited
    15,067       *       15,067              
Citigroup Employee Fund of Funds (Master Fund) I, L.P.
    14,980       *       14,980              
The New Mexico State Investment Council Severance Tax Permanent Fund
    14,919       *       14,919              
Employees’ Retirement System of the State of Hawaii, by Abbott Capital Management, LLC, its Investment Manager
    13,776       *       13,776              
Ewing Marion Kauffman Foundation
    13,776       *       13,776              
Nortel Networks, Inc.
    13,776       *       13,776              
AC Private Equity Corp.
    13,561       *       13,561              
Northern Trust Company, Trustee Bristol-Myers Squibb Master Trust
    13,067       *       13,067              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
UBS Global Asset Management Trust Company as Trustee of The Brinson Partnership Fund Trust - 2001 Primary Fund
    12,963       *       12,963              
Alcyon Ltd.
    12,915       *       12,915              
Johns Hopkins University
    12,054       *       12,054              
2000 Champion Ventures (Q), LP
    11,021       *       11,021              
The Travelers Indemnity Company
    10,045       *       10,045              
Adams Street Partnership Fund - 2002 U.S. Fund
    9,723       *       9,723              
Pratt Street Ventures XIII, LLC
    9,040       *       9,040              
Frank Russell Global Private Equity Fund of Funds, L.P.
    8,610       *       8,610              
The Bunting Family II, LLC
    8,610       *       8,610              
California Institute of Technology
    8,610       *       8,610              
Carnegie Mellon University
    8,610       *       8,610              
Trustees of the Cheyne Walk Trust
    8,610       *       8,610              
Community Foundation Silicon Valley
    8,610       *       8,610              
Glenmede Private Equity Fund II LLC
    8,610       *       8,610              
G. Grandchildren 1986 Trust George P. Levendis, Trustee
    8,610       *       8,610              
Northern Trust Company as Trustee for the Illinois Municipal Retirement Fund, by Abbott Capital Management, LLC, its Investment Manager
    8,610       *       8,610              
The James Irvine Foundation
    8,610       *       8,610              
Board of Fire & Police Pensions Commissioners of the City of Los Angeles, by Abbott Capital Management, LLC, as Investment Manager
    8,610       *       8,610              
Munder NetNet Fund, a series of The Munder Funds, Inc.
    8,610       *       8,610              
Novell, Inc.
    8,610       *       8,610              
Pension Private Equity K/S II
    8,610       *       8,610              
University of Pittsburgh — of the Commonwealth System of Higher Education
    8,610       *       8,610              
The Northern Trust Company as Trustee of the Vulcan Materials Company Master Pension Trust
    8,610       *       8,610              
University of Washington
    8,610       *       8,610              
Capita Trust Company Limited as Trustee of Westport US Private Equity Fund II
    8,610       *       8,610              
The President and Trustees of Williams College
    8,610       *       8,610              
Wilshire Australia Private Markets Fund
    8,610       *       8,610              
Wilshire IAM Fund, L.P.
    8,610       *       8,610              
Commerce & Industry Company
    7,850       *       7,850              
HarbourVest Partners VI-Parallel Partnership Fund L.P.
    7,749       *       7,749              
EFG Trust II, Edward M. Glassmeyer, Trustee
    7,534       *       7,534              
Emont Ltd.
    7,534       *       7,534              
522 Fifth Avenue Fund, L.P.
    7,517       *       7,517              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
UBS Global Asset Management Trust Company as Trustee of The Brinson Partnership Fund Trust - 2002 Secondary Fund
    6,956       *       6,956              
Trustees of Amherst College
    6,888       *       6,888              
Trustees of Boston University
    6,888       *       6,888              
Kleinwort Benson (Channel Islands) Limited as Custodian for MC Partners Limited
    6,888       *       6,888              
Frank Russell Capital/OMERS, L.P.
    6,888       *       6,888              
Private Equity Access Fund II, LLC
    6,780       *       6,780              
David A. Stamm
    6,780       *       6,780              
Bayview (NEA10), L.P.
    6,629       *       6,629              
Thomas Weisel Global Growth Partners (A), L.P.
    6,280       *       6,280              
Katherine S. Ingalls
    6,027       *       6,027              
James T. McManus
    6,027       *       6,027              
O-S Ventures
    6,027       *       6,027              
Theresa W. and Robert J. Ryan, Joint Tenants
    6,027       *       6,027              
Bayview 2000, L.P.
    6,027       *       6,027              
Joshua S. Boger
    6,027       *       6,027              
Edward M. Cluss, Jr. and Patricia A. Cluss
    6,027       *       6,027              
FEA II, L.P.
    6,027       *       6,027              
Fox Family Portfolio Partnership
    6,027       *       6,027              
Legacy I, LLC
    6,027       *       6,027              
The Queen’s Health Systems
    6,027       *       6,027              
Saal Family Partners, L.P.
    6,027       *       6,027              
Pradeep S. Sindhu
    6,027       *       6,027              
Board of Trustees of the Leland Stanford Junior University
    6,027       *       6,027              
Zisman Equities Group, L.P.
    6,027       *       6,027              
Brinson Partnership Fund Program Entity A
    5,875       *       5,875              
Standish Ventures V LLC
    5,756       *       5,756              
Morris Ventures
    5,726       *       5,726              
B&S 2002-C GmbH
    5,682       *       5,682              
Lauer & Co. Agent for: Pew Memorial Trust
    5,682       *       5,682              
Brinson Partnership Fund - 2001 Primary Fund, L.P.
    5,393       *       5,393              
Alps Investment LLC
    5,166       *       5,166              
Paul or Evelyn Baran, as trustee of the PAUL AND EVELYN BARAN AGRMT of 23 May 1984
    5,166       *       5,166              
Calconn Private Equities II, LLC
    5,166       *       5,166              
Munder Future Technology Fund, a series of The Munder Funds, Inc.
    5,166       *       5,166              
PEI Capital Partners, L.P. II
    5,166       *       5,166              
Pension Plan of Piper Marbury Rudnick & Wolfe LLP
    5,166       *       5,166              
Rensselaer Polytechnic Institute
    5,166       *       5,166              
The Rose Hills Foundation
    5,166       *       5,166              
Stuart Foundation
    5,166       *       5,166              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Walton Investment IV, LLC
    5,166       *       5,166              
The Travelers Insurance Company
    5,022       *       5,022              
KFLP-II Limited Partnership
    4,821       *       4,821              
ING Pomona Private Equity Fund
    4,773       *       4,773              
Woodbrook MB LP
    4,735       *       4,735              
Hobart Family Limited #7
    4,520       *       4,520              
EDS Retirement Plan Trust
    4,518       *       4,518              
PEI Capital Partners, L.P.
    4,305       *       4,305              
The 2001 Primary Brinson Partnership Fund Offshore Series Company Ltd.
    4,116       *       4,116              
Picotte Venture Capital Fund I, LLC
    3,616       *       3,616              
Private Equity Portfolio Technology Fund, LLC
    3,616       *       3,616              
State Universities Retirement System
    7,344       *       3,444       3,900       *  
Iceship & Co. by State Street Bank & Trust Co. as Trustee for the Brown & Williamson Tobacco Master Retirement Plan
    3,444       *       3,444              
Caravan Trust
    3,444       *       3,444              
Comerica Capital Advisors Incorporated
    3,444       *       3,444              
Siguler Guff Advisors, L.L.C. on behalf of a client
    3,444       *       3,444              
Munder @ Vantage Fund
    3,444       *       3,444              
Timothy J. Rink
    3,444       *       3,444              
Stewardship Foundation
    3,444       *       3,444              
Venture Capital Private Equity Fund
    3,444       *       3,444              
Thomas Weisel Strategic Opportunities Partners, L.P.
    3,444       *       3,444              
Pomona Partnership Holdings III, LP
    3,373       *       3,373              
Cornish & Carey Commercial Venture Fund, LLC
    3,013       *       3,013              
Jennifer Bergantino
    3,013       *       3,013              
Dahl Family Trust dated 10/31/89 as amended 5/3/90, Robert K Dahl, trustee
    3,013       *       3,013              
Giancarlo Family Trust U/D/T 11/2/98, Charles Giancarlo, Trustee
    3,013       *       3,013              
Malcolm Hecht, Jr. Revocable Trust B
    3,013       *       3,013              
Hemant Kanakia
    3,013       *       3,013              
Hemant Kanakia, GRAT
    3,013       *       3,013              
Mario M. Morino Trust
    3,013       *       3,013              
Family Neukermans Trust U/A DTD 01/21/93 Armand Neukermans & Eliane Neukermans, Trustees
    3,013       *       3,013              
James D. Norrod
    3,013       *       3,013              
The Pivotal Trust dated 7/20/2000
    3,013       *       3,013              
A. Brooke Seawell
    3,013       *       3,013              
D.R. Stephens Separate Property Trust UAD May 1, 1983 D.R Stephens, Trustee
    3,013       *       3,013              
Jeannette Symons Living Trust
    3,013       *       3,013              
Richard L. Thompson
    3,013       *       3,013              
Phil White
    3,013       *       3,013              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
John M. McQuillan IRA Rollover
    3,013       *       3,013              
Joseph W. Alsop
    3,013       *       3,013              
Morteza Ejabat Trust
    3,013       *       3,013              
Robert A. Ellis Revocable Trust
    3,013       *       3,013              
Michael J. Homer, Trust
    3,013       *       3,013              
K&M Family Partners Ltd.
    3,013       *       3,013              
Leslie Investments, LLC
    3,013       *       3,013              
Jonathan MacQuitty
    3,013       *       3,013              
The Poizner Family Trust dated 3/3/98, Stephen L. Poizner, Trustee
    3,013       *       3,013              
Saal Family Foundation
    3,013       *       3,013              
Thomas H. Scholl
    3,013       *       3,013              
Tomasetta Family Partnership, L.P.
    3,013       *       3,013              
2000 Champion Ventures, LP
    2,755       *       2,755              
Brinson Partnership Fund - 2002 Secondary Fund, L.P.
    2,672       *       2,672              
Orange County Employees Retirement System
    2,583       *       2,583              
The 2002 Secondary Brinson Partnership Fund Offshore Series Company Ltd.
    2,260       *       2,260              
Northern Trust Bank as Trustee for W. Clement Stone Children’s Trust Norman C. Stone Trust Share
    2,260       *       2,260              
Avondale LLC
    2,260       *       2,260              
Whitemarsh Associates
    2,260       *       2,260              
DLJ Multi-Manager Private Equity Fund, L.P.
    2,135       *       2,135              
Erik T. Engelson, Trustee of the Erik T. Engelson Trust UDT, dated March 29, 2000
    1,958       *       1,958              
ABB Anlagestiftung — Private Equity World 1
    1,722       *       1,722              
BDB Family L.P.
    1,722       *       1,722              
BNA Associates, L.P.
    1,722       *       1,722              
Mary Morse Cargill Revocable Trust
    1,722       *       1,722              
Chestnut Investor, LLC
    1,722       *       1,722              
Entrepreneurs Endowment Fund LLC
    1,722       *       1,722              
Glynn Investment Co. LLC
    1,722       *       1,722              
KKP Holdings LLC
    1,722       *       1,722              
Meresman Investments LLC
    1,722       *       1,722              
Living Trust of Stephens F. Millard 9/16/91
    1,722       *       1,722              
Morgan Venture Fund LLC
    1,722       *       1,722              
Quattrone Family Trust UTA DTD 9/4/91
    1,722       *       1,722              
Kanwal S. Rekhi and Ann H Rekhi as Trustees of the Rekhi Family Trust DTD 12/15/89
    1,722       *       1,722              
Trustees of the Ronald Family Trust B
    1,722       *       1,722              
The Rector & Visitors of the University of Virginia (B)
    1,722       *       1,722              
Boston & Co. A/C# WERF 1963002
    1,722       *       1,722              
Francis H. Zenie
    1,722       *       1,722              
Bayshore Boulevard Associates, LLC
    1,507       *       1,507              
Boutros Family Trust UAD 5/23/00
    1,507       *       1,507              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
William J.B. Brady III
    1,507       *       1,507              
Arthur & Barbara Friedman Revocable Trust
    1,507       *       1,507              
Marion H. MacMillan Family Trust
    1,507       *       1,507              
Metcalfe Family Trust, John Metcalfe and Valerie Metcalfe, Trustees
    1,507       *       1,507              
1996 Stradford-Wunderlich Rev. Trust
    1,507       *       1,507              
The Alexander Living Trust
    1,507       *       1,507              
Kim B. Edwards
    1,507       *       1,507              
Francine Gani 2002 Living Trust
    1,507       *       1,507              
Marcel Gani 2002 Living Trust
    1,507       *       1,507              
Daniel L. Harple, Jr.
    1,507       *       1,507              
The JGA Trust under agreement dtd 9/18/00, Joseph Ansanelli, Trustee
    1,507       *       1,507              
Mahendra Kaul
    1,507       *       1,507              
Bernard M. Kramer, M.D., Inc. Profit Sharing Plan
    1,507       *       1,507              
Milagro de Ladera, L.P.
    1,507       *       1,507              
Sara Ostrofsky
    1,507       *       1,507              
Ronald S. Posner
    1,507       *       1,507              
The Ramsay Family Trust DTD 10/17/94
    1,507       *       1,507              
N & A Raza Revocable Trust UAD 03-22-97
    1,507       *       1,507              
Stone Family Trust — Share B
    1,507       *       1,507              
Robert P. Taylor and Anne D. Kaiser
    1,507       *       1,507              
Ronald J. Vidal
    1,507       *       1,507              
Yock Family Revocable Trust Dated 7/21/93 as the Separate Property of Paul G. Yock
    1,507       *       1,507              
Thiry-O’Leary Living Trust Dated March 8, 1990
    1,378       *       1,378              
Emerson Street Ventures, a California Limited Partnership
    1,291       *       1,291              
Michael E. Herman Revocable Trust
    1,291       *       1,291              
Frank M. Fischer
    1,206       *       1,206              
Paul C. Nehra, MD
    1,206       *       1,206              
Lauer & Co. Agent for: J.H. Pew Freedom Trust
    1,205       *       1,205              
DLJ PEP II Employee Fund, L.P.
    1,180       *       1,180              
Buuck Family Limited Partnership by Wells Fargo Bank MN N.A as custodian for Robert E Buuck, General Partner
    1,119       *       1,119              
Richard M. Berkeley
    1,055       *       1,055              
R. David Dicioccio, Jr.
    1,055       *       1,055              
Malcolm Hecht, Jr. Revocable Trust A
    904       *       904              
Robert W. Frick
    904       *       904              
George Trust dated 7/27/00
    904       *       904              
Pivan Nigam and Ruma Nigam, Co-Trustees of the Nigam Living Trust u/t/a dated September 16, 1999
    904       *       904              
Robert K. Anderson
    861       *       861              
Rod A. Beckstrom Trust U/D/T 11/21/95
    861       *       861              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Gary Bowen
    861       *       861              
BPE Institutional Partners G.m.b.H
    861       *       861              
Gregory 1993 Investment Trust U/A DTD 7/21/93, David J Gregory, Trustee
    861       *       861              
Hillcrest Capital Investors LLC
    861       *       861              
Komisar/Dunn Family Trust
    861       *       861              
Jay T. Last
    861       *       861              
Menlo School
    861       *       861              
William G. Myers Roth IRA
    861       *       861              
Orion QP Ventures III L.P.
    861       *       861              
Marc Ostrofsky
    861       *       861              
Henry A. Plain, Jr. and Lisa M. Plain, Trustees The Plain Family Trust, U/D/T dated September 7, 1994
    861       *       861              
Neil J. Rappaport and Susan J. Rappaport, Trustee of the Rappaport Family rust, dated March 31, 1997
    861       *       861              
John T. Sakai
    861       *       861              
Daniel S. Simpkins
    861       *       861              
Swingyer Partners
    861       *       861              
Lauer & Co. Agent for: Mabel Pew Myrin Trust
    775       *       775              
International Capital Partners, Inc. Profit-Sharing Trust
    753       *       753              
44 Eastview Family LLC
    753       *       753              
Sanjiv Ahuja
    753       *       753              
Bernal Family Trust UDT dated November 3, 1995, Ronald Daniel Bernal & Pamela Mayer Bernal Trustees
    753       *       753              
Robert J. Carpenter
    753       *       753              
Gayle Crowell
    753       *       753              
Kirk A. Cruikshank & Bette Lee Cruikshank, Trustees, Cruikshank Family Trust 10/1/97
    753       *       753              
Stuart M. Gordon
    753       *       753              
The Gregory C. Gretsch Trust, Gregory C. Gretsch, Trustee
    753       *       753              
Joe E. Kiani
    753       *       753              
Stanard T. Klinefelter
    753       *       753              
John R. Mashey
    753       *       753              
James A. McDonald
    753       *       753              
The Parulkar Family Revocable Trust of 12/29/99, Guru
                                       
Parulkar, Trustee
    753       *       753              
WUCO Capital LLC
    753       *       753              
Donald L. Thiry Trust dated 4/7/82
    689       *       689              
Buuck Family Foundation by Wells Fargo Bank MN N.A. as Agent for Robert E. Buuck, President
    603       *       603              
Lauer & Co. Agent for : J.N. Pew Trust
    603       *       603              
Julian A. Brodsky
    602       *       602              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
Van Dyke Partners
    602       *       602              
James W. Bullock
    602       *       602              
David Cheriton
    602       *       602              
James Friedman
    602       *       602              
Michael D. Lesh
    602       *       602              
Seth Lieber
    602       *       602              
Francis A. Moody
    602       *       602              
The Babak & Lisa Marie Yazdani Trust UTA dtd 4/27/00
    602       *       602              
Paul L.Gomory, Jr. Trust
    517       *       517              
G. Kirk Raab
    517       *       517              
Meng Partners
    452       *       452              
Daniel P. Finkelman
    452       *       452              
Mohammed N. Islam
    452       *       452              
Robert J. McGovern
    452       *       452              
Maurice Werdegar
    1,930       *       430       1,500       *  
Brody Family Trust U/T/D 8/15/86
    430       *       430              
Daniel Burstein
    430       *       430              
Chadwick H. Carpenter, Jr.
    430       *       430              
Key Capital Corporation
    430       *       430              
Sheila R. Kresch
    430       *       430              
Thomas H. Layton or his sucessor under the Thomas H. Layton Separate Property Revocable Trust, November 29, 1999, as amended
    430       *       430              
Joseph A. Liemandt
    430       *       430              
Audrey MacLean and Michael Clair, as trustees, or their successors, of the Audrey MacLean and Michael Clair Trust
                                       
Agreement UAD 12/1/90
    430       *       430              
Makower Family Trust U/D/T dated 5/6/97
    430       *       430              
Trust u/w William C. Whitridge
    430       *       430              
Peter D. Behrendt
    376       *       376              
Peter D. Fenner & Nancy R. Fenner, as Trustees of the Peter D. Fenner & Nancy R. Fenner Living Trust dated 2/2/99
    344       *       344              
Fontaine Revocable Living Trust DTD 3/23/84
    344       *       344              
Lauer & Co. Agent for: The Medical Trust
    344       *       344              
The Edward C. Oldfield, Jr. RLT dtd 11-18-96 Edward C Oldfield, Jr. Trustee
    344       *       344              
Ramaswami Family Revocable Trust
    344       *       344              
Vrolyk Family Trust U/A DTD 11/20/84, as amended John R. and Tamisie Honey Vrolyk, Trustees
    344       *       344              
Barbara A. Cannon
    301       *       301              
Silverleaf Partners LLC
    301       *       301              
The Per A. Suneby Revocable Trust
    301       *       301              
Horst R. Adam
    301       *       301              
William Michael Fagen
    301       *       301              

 


 

                                         
                    Number of Shares Being                
    Shares Owned Prior to Offering   Offered   Shares Owned After Offering
   
 
 
Security Holders   Number (1)   Percent (1)           Number   Percent (2)

 
 
         
 
David F. Foster
    301       *       301              
Hsing-Chung Lee
    301       *       301              
Oak Stone Ventures, LLC
    301       *       301              
Orlando W. Springs
    301       *       301              
Richard A. Redelfs
    258       *       258              
The Goodman Family Trust
    172       *       172              
Kamran Sistanizadeh
    172       *       172              
Wilshire U.S. Private Markets Fund IV, L.P. (B)
    172       *       172              
Stanford T. and Donna M. Young, as community property
    172       *       172              
522 Fifth Avenue Fund, L.P. - 2002 Program
    114       *       114              


*   Less than one percent (1%)
 
(1)   The shares of common stock owned prior to the offering equals the sum of (a) shares of common stock, (b) shares of common stock issuable upon conversion of shares of Series A preferred stock and (c) shares of common stock issuable upon exercise of warrants. Percentages are based on 59,203,660 shares of our common stock that were outstanding (on an as-converted to common stock basis) on June 17, 2003. In calculating the percentage for each selling security holder, the shares represented by item (b) above are included in the denominator of the shares outstanding for that selling security holder but are not included in the denominator for any other person.
 
(2)   Percentages are based on 59,203,660 shares of our common stock that were outstanding (on an as-converted to common stock basis) on June 17, 2003.
 
(3)   Includes 170,885 shares of common stock issuable upon exercise of warrants.
 
(4)   Includes 2,448,562 shares of common stock issuable upon exercise of warrants (including a warrant to purchase 2,198,605 shares of common stock received in connection with the warrant repricing agreement), , including warrants to purchase 999 shares of common stock held by NEA Ventures 2001, L.P. In addition, includes 9,998 shares held by NEA Ventures 2001, L.P. Also includes 1,033,057 shares of our Series A Preferred Stock that are convertible at any time into 4,132,228 shares of Common Stock. According to a Schedule 13D Amendment No. 1 dated April 25, 2002, and filed jointly by New Enterprise Associates 10, Limited Partnership (“NEA 10”), NEA Partners 10, Limited Partnership, Stewart Alsop, James Barrett, Peter J. Barris, Robert T. Coneybeer, Nancy L. Dorman, Ronald H. Kase, C. Richard Kramlich, Thomas C. McConnell, Peter T. Morris, Charles W. Newhall III, Mark W. Perry, Scott D. Sandell and Eugene A. Trainor III, each of the aforementioned general partners of NEA 10 has shared dispositive and shared voting power with respect to the shares held by NEA 10. Each of the aforementioned disclaims beneficial ownership as to the shares held by NEA 10, except to the extent of their pecuniary interest therein. John Nehra is a member of our board of directors and a limited partner of NEA Partners 10, Limited Partnership, the general partner of NEA 10.

     We may from time to time supplement or amend the Prospectus to reflect the required information concerning and transferee, pledgee, donee or successor to the selling security holders named in the prospectus.

The date of this Prospectus Supplement is June 20, 2003.