Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-21213         

        Nuveen Insured Tax-Free Advantage Municipal Fund         
(Exact name of registrant as specified in charter)

Nuveen Investments
        333 West Wacker Drive, Chicago, Illinois 60606         
(Address of principal executive offices) (Zip code)


Jessica R. Droeger—Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         
(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            10/31          

Date of reporting period:         1/31/07         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget (“OMB”) control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

    Portfolio of Investments (Unaudited)             
    Nuveen Insured Tax-Free Advantage Municipal Fund (NEA)             
    January 31, 2007             
Principal        Optional Call         
Amount (000)    Description (1)    Provisions (2)    Ratings (3)    Value 
    Alabama – 8.3% (5.5% of Total Investments)             
$          5,655    Colbert County-Northwest Health Care Authority, Alabama, Revenue Bonds, Helen Keller Hospital,    6/13 at 101.00    Baa3   $   5,917,562 
     Series 2003, 5.750%, 6/01/27             
3,100    Huntsville Healthcare Authority, Alabama, Revenue Bonds, Series 1998A, 5.400%, 6/01/22 – MBIA    5/12 at 102.00    AAA    3,345,458 
     Insured             
6,280    Jefferson County, Alabama, Sewer Revenue Capital Improvement Warrants, Series 2002D, 5.000%,    8/12 at 100.00    AAA    6,646,061 
     2/01/32 (Pre-refunded 8/01/12) – FGIC Insured             
1,750    Montgomery, Alabama, General Obligation Warrants, Series 2003, 5.000%, 5/01/21 – AMBAC Insured    5/12 at 101.00    AAA    1,849,225 
4,500    Sheffield, Alabama, Electric Revenue Bonds, Series 2003, 5.500%, 7/01/29 – AMBAC Insured    7/13 at 100.00    Aaa    4,827,870 
21,285    Total Alabama            22,586,176 
    Arizona – 3.8% (2.5% of Total Investments)             
10,000    Maricopa County Pollution Control Corporation, Arizona, Revenue Bonds, Arizona Public Service    11/12 at 100.00    AAA    10,409,900 
     Company – Palo Verde Project, Series 2002A, 5.050%, 5/01/29 – AMBAC Insured             
    California – 29.0% (19.1% of Total Investments)             
26,300    California State Public Works Board, Lease Revenue Bonds, Department of General Services,    12/12 at 100.00    AAA    27,376,982 
     Capital East End Project, Series 2002A, 5.000%, 12/01/27 – AMBAC Insured             
7,500    California, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 – AMBAC Insured    4/14 at 100.00    AAA    7,851,075 
13,500    California, General Obligation Refunding Bonds, Series 2002, 5.250%, 4/01/30 – XLCA Insured    4/12 at 100.00    AAA    14,234,805 
2,910    Cathedral City Public Financing Authority, California, Tax Allocation Bonds, Housing    8/12 at 102.00    AAA    3,055,587 
     Set-Aside, Series 2002D, 5.000%, 8/01/26 – MBIA Insured             
2,500    Irvine Public Facilities and Infrastructure Authority, California, Assessment Revenue Bonds,    3/07 at 103.00    AAA    2,576,225 
     Series 2003C, 5.000%, 9/02/23 – AMBAC Insured             
4,000    Montara Sanitation District, California, General Obligation Bonds, Series 2003, 5.000%,    8/11 at 101.00    AAA    4,165,640 
     8/01/28 – FGIC Insured             
    Plumas County, California, Certificates of Participation, Capital Improvement Program, Series             
    2003A:             
1,130     5.250%, 6/01/19 – AMBAC Insured    6/13 at 101.00    AAA    1,217,134 
1,255     5.250%, 6/01/21 – AMBAC Insured    6/13 at 101.00    AAA    1,347,694 
1,210    Redding Joint Powers Financing Authority, California, Lease Revenue Bonds, Capital Improvement    3/13 at 100.00    AAA    1,256,936 
     Projects, Series 2003A, 5.000%, 3/01/23 – AMBAC Insured             
3,750    Sacramento Municipal Utility District, California, Electric Revenue Bonds, Series 2003R,    8/13 at 100.00    AAA    3,927,563 
     5.000%, 8/15/28 – MBIA Insured             
1,500    San Diego Community College District, California, General Obligation Bonds, Series 2003A,    5/13 at 100.00    AAA    1,566,945 
     5.000%, 5/01/28 – FSA Insured             
3,000    San Jose Redevelopment Agency, California, Tax Allocation Bonds, Merged Area Redevelopment    8/10 at 101.00    AAA    3,166,290 
     Project, Series 2002, 5.000%, 8/01/32 (Pre-refunded 8/01/10) – MBIA Insured             
1,055    Turlock Irrigation District, California, Certificates of Participation, Series 2003A, 5.000%,    1/13 at 100.00    AAA    1,097,369 
     1/01/28 – MBIA Insured             
6,300    University of California, Revenue Bonds, Multi-Purpose Projects, Series 2003A, 5.000%,    5/13 at 100.00    AAA    6,582,744 
     5/15/33 – AMBAC Insured             
75,910    Total California            79,422,989 
    Colorado – 3.8% (2.5% of Total Investments)             
    Bowles Metropolitan District, Colorado, General Obligation Bonds, Series 2003:             
4,300     5.500%, 12/01/23 – FSA Insured    12/13 at 100.00    AAA    4,682,055 
3,750     5.500%, 12/01/28 – FSA Insured    12/13 at 100.00    AAA    4,059,900 
1,450    Colorado Educational and Cultural Facilities Authority, Charter School Revenue Bonds,    8/14 at 100.00    AAA    1,547,005 
     Peak-to-Peak Charter School, Series 2004, 5.250%, 8/15/24 – XLCA Insured             
9,500    Total Colorado            10,288,960 
    Florida – 1.2% (0.8% of Total Investments)             
3,000    Pinellas County Health Facilities Authority, Florida, Revenue Bonds, Baycare Health System,    5/13 at 100.00    Aa3 (4)    3,269,580 
     Series 2003, 5.500%, 11/15/27 (Pre-refunded 5/15/13)             
    Georgia – 2.0% (1.3% of Total Investments)             
1,410    DeKalb County, Georgia, Water and Sewer Revenue Bonds, Series 2006A, 5.000%, 10/01/35 – FSA    10/16 at 100.00    AAA    1,493,613 
     Insured             
3,825    Metropolitan Atlanta Rapid Transit Authority, Georgia, Sales Tax Revenue Bonds, Second    1/13 at 100.00    AAA    3,987,792 
     Indenture Series 2002, 5.000%, 7/01/32 – MBIA Insured             
5,235    Total Georgia            5,481,405 
    Illinois – 3.7% (2.5% of Total Investments)             
905    Cook County School District 100, Berwyn South, Illinois, General Obligation Refunding Bonds,    12/13 at 100.00    Aaa    984,124 
     Series 2003B, 5.250%, 12/01/21 (Pre-refunded 12/01/13) – FSA Insured             
    Cook County School District 145, Arbor Park, Illinois, General Obligation Bonds, Series 2004:             
3,285     5.125%, 12/01/20 – FSA Insured    12/14 at 100.00    Aaa    3,512,092 
2,940     5.125%, 12/01/23 – FSA Insured    12/14 at 100.00    Aaa    3,127,249 
2,500    Illinois Health Facilities Authority, Revenue Bonds, Lake Forest Hospital, Series 2003,    7/13 at 100.00    A–    2,597,750 
     5.250%, 7/01/23             
9,630    Total Illinois            10,221,215 
    Indiana – 8.8% (5.8% of Total Investments)             
2,500    Evansville, Indiana, Sewerage Works Revenue Refunding Bonds, Series 2003A, 5.000%, 7/01/23 –    7/13 at 100.00    AAA    2,625,725 
     AMBAC Insured             
2,190    Indiana Bond Bank, Advance Purchase Funding Bonds, Common School Fund, Series 2003B, 5.000%,    8/13 at 100.00    AAA    2,305,172 
     8/01/19 – MBIA Insured             
1,000    Indiana University, Student Fee Revenue Bonds, Series 2003O, 5.000%, 8/01/22 – FGIC Insured    8/13 at 100.00    AAA    1,053,230 
    IPS Multi-School Building Corporation, Indiana, First Mortgage Revenue Bonds, Series 2003:             
11,020     5.000%, 7/15/19 – MBIA Insured    7/13 at 100.00    AAA    11,638,112 
6,000     5.000%, 7/15/20 – MBIA Insured    7/13 at 100.00    AAA    6,336,540 
22,710    Total Indiana            23,958,779 
    Kansas – 2.4% (1.6% of Total Investments)             
6,250    Kansas Development Finance Authority, Board of Regents, Revenue Bonds, Scientific Research and    4/13 at 102.00    AAA    6,641,938 
     Development Facilities Projects, Series 2003C, 5.000%, 10/01/22 – AMBAC Insured             
    Kentucky – 0.3% (0.3% of Total Investments)             
985    Kentucky State Property and Buildings Commission, Revenue Refunding Bonds, Project 77, Series    8/13 at 100.00    AAA    1,053,389 
     2003, 5.000%, 8/01/23 (Pre-refunded 8/01/13) – MBIA Insured             
    Louisiana – 2.2% (1.5% of Total Investments)             
5,785    New Orleans, Louisiana, General Obligation Refunding Bonds, Series 2002, 5.300%, 12/01/27 –    12/12 at 100.00    AAA    6,095,250 
     FGIC Insured             
    Massachusetts – 5.0% (3.3% of Total Investments)             
9,000    Massachusetts Bay Transportation Authority, Senior Sales Tax Revenue Refunding Bonds, Series    7/12 at 100.00    AAA    9,544,320 
     2002A, 5.000%, 7/01/27 (Pre-refunded 7/01/12) – FGIC Insured             
1,125    Massachusetts Development Finance Authority, Revenue Bonds, Middlesex School, Series 2003,    9/13 at 100.00    A1    1,178,010 
     5.125%, 9/01/23             
3,000    Massachusetts Turnpike Authority, Metropolitan Highway System Revenue Bonds, Senior Series    7/07 at 102.00    AAA    3,045,870 
     1997A, 5.000%, 1/01/37 – MBIA Insured             
13,125    Total Massachusetts            13,768,200 
    Michigan – 11.6% (7.6% of Total Investments)             
6,130    Detroit, Michigan, Senior Lien Water Supply System Revenue Bonds, Series 2003A, 5.000%,    7/13 at 100.00    AAA    6,550,579 
     7/01/23 (Pre-refunded 7/01/13) – MBIA Insured             
4,465    Detroit, Michigan, Senior Lien Water Supply System Revenue Refunding Bonds, Series 2003C,    7/13 at 100.00    AAA    4,699,859 
     5.000%, 7/01/22 – MBIA Insured             
10,800    Michigan Strategic Fund, Limited Obligation Resource Recovery Revenue Refunding Bonds, Detroit    12/12 at 100.00    AAA    11,341,188 
     Edison Company, Series 2002D, 5.250%, 12/15/32 – XLCA Insured             
2,250    Romulus Community Schools, Wayne County, Michigan, General Obligation Refunding Bonds, Series    5/11 at 100.00    AA    2,355,188 
     2001, 5.250%, 5/01/25             
6,500    Wayne County, Michigan, Limited Tax General Obligation Airport Hotel Revenue Bonds, Detroit    12/11 at 101.00    AAA    6,764,485 
     Metropolitan Wayne County Airport, Series 2001A, 5.000%, 12/01/30 – MBIA Insured 
30,145    Total Michigan            31,711,299 
    Missouri – 1.1% (0.7% of Total Investments)             
240    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    258,338 
     2004, 5.250%, 3/01/24 – FSA Insured             
215    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    231,428 
     2004, 5.250%, 3/01/23 – FSA Insured             
    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series             
    2004:             
1,110     5.250%, 3/01/23 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,207,303 
1,260     5.250%, 3/01/24 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,370,452 
2,825    Total Missouri            3,067,521 
    Nebraska – 1.9% (1.3% of Total Investments)             
5,000    Lincoln, Nebraska, Sanitary Sewerage System Revenue Refunding Bonds, Series 2003, 5.000%,    6/13 at 100.00    AAA    5,227,050 
     6/15/28 – MBIA Insured             
    Nevada – 0.9% (0.6% of Total Investments)             
2,315    Clark County, Nevada, Subordinate Lien Airport Revenue Bonds, Series 2001B, 5.200%, 7/01/31    7/11 at 100.00    AAA    2,447,974 
     (Pre-refunded 7/01/11) – FGIC Insured             
    New Mexico – 0.8% (0.5% of Total Investments)             
1,975    New Mexico State University, Revenue Bonds, Series 2004, 5.000%, 4/01/19 – AMBAC Insured    4/14 at 100.00    AAA    2,092,236 
    New York – 10.9% (7.2% of Total Investments)             
2,020    Hudson Yards Infrastructure Corporation, New York, Revenue Bonds, Series 2006, 4.500%, 2/15/47 –     2/17 at 100.00    AAA    1,997,396 
     MBIA Insured (UB)             
25,000    Metropolitan Transportation Authority, New York, Transportation Revenue Refunding Bonds,    11/12 at 100.00    AAA    26,095,250 
     Series 2002F, 5.000%, 11/15/31 – MBIA Insured             
1,850    New York State Urban Development Corporation, Service Contract Revenue Bonds, Series 2005B,    3/15 at 100.00    AAA    1,956,745 
     5.000%, 3/15/25 – FSA Insured             
28,870    Total New York            30,049,391 
    North Carolina – 3.4% (2.2% of Total Investments)             
8,700    North Carolina Medical Care Commission, Revenue Bonds, Maria Parham Medical Center, Series    10/13 at 100.00    AA    9,197,814 
     2003, 5.375%, 10/01/33 – RAAI Insured             
    Oklahoma – 0.4% (0.3% of Total Investments)             
1,000    Oklahoma Capitol Improvement Authority, State Facilities Revenue Bonds, Series 2005F, 5.000%,    7/15 at 100.00    AAA    1,060,200 
     7/01/24 – AMBAC Insured             
    Oregon – 3.2% (2.1% of Total Investments)             
8,350    Oregon Health Sciences University, Revenue Bonds, Series 2002A, 5.000%, 7/01/32 – MBIA Insured    1/13 at 100.00    AAA    8,705,376 
    Pennsylvania – 8.9% (5.8% of Total Investments)             
3,000    Lehigh County General Purpose Authority, Pennsylvania, Hospital Revenue Bonds, St. Luke’s    8/13 at 100.00    Baa1    3,138,570 
     Hospital of Bethlehem, Series 2003, 5.375%, 8/15/33             
2,000    Philadelphia Gas Works, Pennsylvania, Revenue Bonds, General Ordinance, Fourth Series 1998,    8/13 at 100.00    AAA    2,080,380 
     5.000%, 8/01/32 – FSA Insured             
925    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%,    8/07 at 102.00    AAA    946,534 
     8/01/27 – AMBAC Insured (ETM)             
4,075    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%,    8/07 at 102.00    AAA    4,175,938 
     8/01/27 – AMBAC Insured             
13,000    State Public School Building Authority, Pennsylvania, Lease Revenue Bonds, Philadelphia School    6/13 at 100.00    AAA    13,896,610 
     District, Series 2003, 5.000%, 6/01/33 (Pre-refunded 6/01/13) – FSA Insured             
23,000    Total Pennsylvania            24,238,032 
    South Carolina – 7.4% (4.9% of Total Investments)             
5,000    Florence County, South Carolina, Hospital Revenue Bonds, McLeod Regional Medical Center,    11/14 at 100.00    AAA    5,345,600 
     Series 2004A, 5.250%, 11/01/23 – FSA Insured             
    Greenville County School District, South Carolina, Installment Purchase Revenue Bonds, Series             
    2003:             
3,000     5.000%, 12/01/22    12/13 at 100.00    AA–    3,127,530 
1,785     5.000%, 12/01/23    12/13 at 100.00    AA–    1,857,667 
1,365    Myrtle Beach, South Carolina, Water and Sewerage System Revenue Refunding Bonds, Series 2003,    3/13 at 100.00    AAA    1,481,899 
     5.375%, 3/01/19 (Pre-refunded 3/01/13) – FGIC Insured             
8,000    South Carolina Transportation Infrastructure Bank, Revenue Bonds, Series 2002A, 5.000%,    10/12 at 100.00    Aaa    8,323,440 
     10/01/33 – AMBAC Insured             
19,150    Total South Carolina            20,136,136 
    Texas – 12.9% (8.5% of Total Investments)             
7,975    Fort Bend Independent School District, Fort Bend County, Texas, General Obligation Bonds,    8/10 at 100.00    AAA    8,203,803 
     Series 2000, 5.000%, 8/15/25             
12,500    Grand Prairie Independent School District, Dallas County, Texas, General Obligation Bonds,    2/13 at 100.00    AAA    13,055,250 
     Series 2003, 5.125%, 2/15/31 – FSA Insured             
2,000    Houston, Texas, First Lien Combined Utility System Revenue Bonds, Series 2004A, 5.250%,    5/14 at 100.00    AAA    2,148,740 
     5/15/25 – MBIA Insured             
5,515    Houston, Texas, General Obligation Refunding Bonds, Series 2002, 5.250%, 3/01/20 – MBIA Insured    3/12 at 100.00    AAA    5,838,179 
5,850    Katy Independent School District, Harris, Fort Bend and Waller Counties, Texas, General    2/12 at 100.00    AAA    6,154,376 
     Obligation Bonds, Series 2002A, 5.125%, 2/15/18             
33,840    Total Texas            35,400,348 
    Virginia – 0.5% (0.4% of Total Investments)             
1,500    Hampton, Virginia, Revenue Bonds, Convention Center Project, Series 2002, 5.125%, 1/15/28 –    1/13 at 100.00    AAA    1,572,255 
     AMBAC Insured             
    Washington – 9.2% (6.0% of Total Investments)             
4,945    Broadway Office Properties, King County, Washington, Lease Revenue Bonds, Washington Project,    12/12 at 100.00    AAA    5,122,921 
     Series 2002, 5.000%, 12/01/31 – MBIA Insured             
5,250    Chelan County Public Utility District 1, Washington, Hydro Consolidated System Revenue Bonds,    7/12 at 100.00    AAA    5,456,588 
     Series 2002C, 5.125%, 7/01/33 – AMBAC Insured             
2,135    Kitsap County Consolidated Housing Authority, Washington, Revenue Bonds, Bremerton Government    7/13 at 100.00    Aaa    2,227,083 
     Center, Series 2003, 5.000%, 7/01/23 – MBIA Insured             
1,935    Pierce County School District 343, Dieringer, Washington, General Obligation Refunding Bonds,    6/13 at 100.00    Aaa    2,073,062 
     Series 2003, 5.250%, 12/01/17 – FGIC Insured             
9,670    Washington State, General Obligation Bonds, Series 2003D, 5.000%, 12/01/21 – MBIA Insured    6/13 at 100.00    AAA    10,183,670 
23,935    Total Washington            25,063,324 
    West Virginia – 1.2% (0.8% of Total Investments)             
3,000    West Virginia State Building Commission, Lease Revenue Refunding Bonds, Regional Jail and    No Opt. Call    AAA    3,376,470 
     Corrections Facility, Series 1998A, 5.375%, 7/01/21 – AMBAC Insured             
    Wisconsin – 6.7% (4.4% of Total Investments)             
1,190    Sun Prairie Area School District, Dane County, Wisconsin, General Obligation Bonds, Series    3/14 at 100.00    Aaa    1,282,070 
     2004C, 5.250%, 3/01/24 – FSA Insured             
4,605    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Franciscan Sisters of    9/13 at 100.00    BBB+    4,914,824 
     Christian Charity Healthcare Ministry, Series 2003A, 5.875%, 9/01/33             
3,000    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Meriter Hospital Inc.,    No Opt. Call    AAA    3,429,720 
     Series 1992A, 6.000%, 12/01/22 – FGIC Insured             
3,600    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Wheaton Franciscan    8/13 at 100.00    A–    3,683,160 
     Services Inc., Series 2003A, 5.125%, 8/15/33             
4,750    Wisconsin Health and Educational Facilities Authority, Revenue Refunding Bonds, Wausau    8/08 at 102.00    AAA    4,913,590 
     Hospital Inc., Series 1998A, 5.125%, 8/15/20 – AMBAC Insured             
17,145    Total Wisconsin            18,223,364 
$      394,165    Total Investments (cost $394,909,902) – 151.5%            414,766,571 
    Floating Rate Obligations (0.5)%            (1,345,000) 
    Other Assets Less Liabilities – 1.6%            4,330,555 
    Preferred Shares, at Liquidation Value – (52.6)%            (144,000,000) 
    Net Assets Applicable to Common Shares – 100%           $   273,752,126 

    At least 80% of the Fund’s net assets (including net assets attributable to Preferred shares) are 
    invested in municipal securities that are either covered by Original Issue Insurance, Secondary 
    Market Insurance or Portfolio Insurance which ensures the timely payment of principal and 
    interest. Up to 20% of the Fund’s net assets (including net assets attributable to Preferred 
    shares) may be invested in municipal securities that are (i) either backed by an escrow or trust 
    containing sufficient U.S. Government or U.S. Government agency securities (also ensuring the 
    timely payment of principal and interest), or (ii) rated, at the time of investment, within the four 
    highest grades (Baa or BBB or better by Moody’s, S&P or Fitch) or unrated but judged to be of 
    comparable quality by the Adviser. 
(1)    All percentages shown in the Portfolio of Investments are based on net assets applicable to 
    Common shares unless otherwise noted. 
(2)    Optional Call Provisions: Dates (month and year) and prices of the earliest optional call or 
    redemption. There may be other call provisions at varying prices at later dates. Certain mortgage 
    -backed securities may be subject to periodic principal paydowns. 
(3)    Ratings: Using the higher of Standard & Poor’s or Moody’s rating. Ratings below BBB by 
    Standard & Poor’s Group or Baa by Moody’s Investor Service, Inc. are considered to be below 
    investment grade. 
(4)    Backed by an escrow or trust containing sufficient U.S. Government or U.S. Government agency 
    securities which ensure the timely payment of principal and interest. Such investments are 
    normally considered to be equivalent to AAA rated securities. 
(ETM)    Escrowed to maturity. 
(UB)    Underlying bond of an inverse floating rate trust reflected as a financing transaction pursuant 
    to the provisions of SFAS No. 140. 

Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to the treatment of paydown gains and losses, timing differences in recognizing taxable market discount, timing differences in recognizing certain gains and losses on investment transactions and the treatment of investments in inverse floating rate transactions subject to SFAS No.140.

At January 31, 2007, the cost of investments was $396,310,779.

Gross unrealized appreciation and gross unrealized depreciation of investments at January 31, 2007, were as follows:

Gross unrealized:     
  Appreciation    $19,932,876 
  Depreciation    (2,822,126) 
Net unrealized appreciation (depreciation) of investments    $17,110,750 

Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: EX-99 CERT Attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Insured Tax-Free Advantage Municipal Fund        

By (Signature and Title)*          /s/ Jessica R. Droeger                     
                                                    Jessica R. Droeger
                                                    Vice President and Secretary

Date         March 30, 2007        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)*         /s/ Gifford R. Zimmerman                    
                                                   Gifford R. Zimmerman
                                                   Chief Administrative Officer (principal executive officer) 

Date         March 30, 2007        

By (Signature and Title)*         /s/ Stephen D. Foy                              
                                                   Stephen D. Foy
                                                   Vice President and Controller (principal financial officer) 

Date        March 30, 2007        

* Print the name and title of each signing officer under his or her signature.