Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-21213         

        Nuveen Insured Tax-Free Advantage Municipal Fund         
(Exact name of registrant as specified in charter)

Nuveen Investments
        333 West Wacker Drive, Chicago, Illinois 60606         

(Address of principal executive offices) (Zip code)


Kevin J. McCarthy Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         

(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            10/31          

Date of reporting period:         1/31/08         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget ("OMB") control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

    Portfolio of Investments (Unaudited)             
    Nuveen Insured Tax-Free Advantage Municipal Fund (NEA)             
    January 31, 2008             
Principal        Optional Call         
Amount (000)    Description (1)    Provisions (2)    Ratings (3)    Value 

    Alabama – 8.6% (5.7% of Total Investments)             
$        1,000    Alabama Special Care Facilities Financing Authority, Revenue Bonds, Ascension Health, Series    11/16 at 100.00    AA   $   1,010,200 
     2006C-2, 5.000%, 11/15/36             
5,655    Colbert County-Northwest Health Care Authority, Alabama, Revenue Bonds, Helen Keller Hospital,    6/13 at 101.00    Baa3    5,638,148 
     Series 2003, 5.750%, 6/01/27             
3,100    Huntsville Healthcare Authority, Alabama, Revenue Bonds, Series 1998A, 5.400%, 6/01/22    5/12 at 102.00    AAA    3,480,990 
     (Pre-refunded 5/14/12) – MBIA Insured             
6,280    Jefferson County, Alabama, Sewer Revenue Capital Improvement Warrants, Series 2002D, 5.000%,    8/12 at 100.00    AAA    6,905,802 
     2/01/32 (Pre-refunded 8/01/12) – FGIC Insured             
1,750    Montgomery, Alabama, General Obligation Warrants, Series 2003, 5.000%, 5/01/21 – AMBAC Insured    5/12 at 101.00    AAA    1,876,595 
4,500    Sheffield, Alabama, Electric Revenue Bonds, Series 2003, 5.500%, 7/01/29 – AMBAC Insured    7/13 at 100.00    Aaa    4,792,230 

22,285    Total Alabama            23,703,965 

    Arizona – 5.6% (3.7% of Total Investments)             
10,000    Maricopa County Pollution Control Corporation, Arizona, Revenue Bonds, Arizona Public Service    11/12 at 100.00    AAA    10,215,000 
     Company – Palo Verde Project, Series 2002A, 5.050%, 5/01/29 – AMBAC Insured             
6,545    Phoenix, Arizona, Civic Improvement Revenue Bonds, Civic Plaza, Series 2005B, 0.000%,    No Opt. Call    Aaa    5,184,622 
     7/01/37 – FGIC Insured             

16,545    Total Arizona            15,399,622 

    California – 26.7% (17.6% of Total Investments)             
26,300    California State Public Works Board, Lease Revenue Bonds, Department of General Services,    12/12 at 100.00    AAA    26,909,893 
     Capital East End Project, Series 2002A, 5.000%, 12/01/27 – AMBAC Insured             
250    California State, General Obligation Bonds, Series 2002, 5.250%, 4/01/30 – XLCA Insured    4/12 at 100.00    AAA    263,323 
10,000    California State, General Obligation Bonds, Series 2002, 5.250%, 4/01/30 (Pre-refunded    4/12 at 100.00    Aaa    11,066,800 
     4/01/12) – XLCA Insured             
5    California State, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 – AMBAC Insured    4/14 at 100.00    AAA    5,025 
7,495    California State, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 (Pre-refunded    4/14 at 100.00    AAA    8,427,153 
     4/01/14) – AMBAC Insured             
2,910    Cathedral City Public Financing Authority, California, Tax Allocation Bonds, Housing    8/12 at 102.00    AAA    3,006,117 
     Set-Aside, Series 2002D, 5.000%, 8/01/26 – MBIA Insured             
250    Golden State Tobacco Securitization Corporation, California, Enhanced Tobacco Settlement    6/17 at 100.00    BBB    216,583 
     Asset-Backed Bonds, Series 2007A-1, 5.125%, 6/01/47             
2,500    Irvine Public Facilities and Infrastructure Authority, California, Assessment Revenue Bonds,    9/13 at 100.00    AAA    2,576,225 
     Series 2003C, 5.000%, 9/02/23 – AMBAC Insured             
4,000    Montara Sanitation District, California, General Obligation Bonds, Series 2003, 5.000%,    8/11 at 101.00    Aaa    4,110,760 
     8/01/28 – FGIC Insured             
    Plumas County, California, Certificates of Participation, Capital Improvement Program,             
    Series 2003A:             
1,130     5.250%, 6/01/19 – AMBAC Insured    6/13 at 101.00    AAA    1,208,060 
1,255     5.250%, 6/01/21 – AMBAC Insured    6/13 at 101.00    AAA    1,328,907 
1,210    Redding Joint Powers Financing Authority, California, Lease Revenue Bonds, Capital Improvement    3/13 at 100.00    AAA    1,260,457 
     Projects, Series 2003A, 5.000%, 3/01/23 – AMBAC Insured             
3,750    Sacramento Municipal Utility District, California, Electric Revenue Bonds, Series 2003R,    8/13 at 100.00    AAA    3,821,625 
     5.000%, 8/15/28 – MBIA Insured             
1,500    San Diego Community College District, California, General Obligation Bonds, Series 2003A,    5/13 at 100.00    AAA    1,565,685 
     5.000%, 5/01/28 – FSA Insured             
1,055    Turlock Irrigation District, California, Certificates of Participation, Series 2003A, 5.000%,    1/13 at 100.00    AAA    1,064,326 
     1/01/28 – MBIA Insured             
6,300    University of California, Revenue Bonds, Multi-Purpose Projects, Series 2003A, 5.000%,    5/13 at 100.00    AAA    6,413,715 
     5/15/33 – AMBAC Insured             

69,910    Total California            73,244,654 

    Colorado – 4.3% (2.8% of Total Investments)             
    Bowles Metropolitan District, Colorado, General Obligation Bonds, Series 2003:             
4,300     5.500%, 12/01/23 – FSA Insured    12/13 at 100.00    AAA    4,716,713 
3,750     5.500%, 12/01/28 – FSA Insured    12/13 at 100.00    AAA    4,086,675 
1,450    Colorado Educational and Cultural Facilities Authority, Charter School Revenue Bonds,    8/14 at 100.00    AAA    1,490,716 
     Peak-to-Peak Charter School, Series 2004, 5.250%, 8/15/24 – XLCA Insured             
3,000    E-470 Public Highway Authority, Colorado, Senior Revenue Bonds, Series 2000B, 0.000%,    No Opt. Call    AAA    837,600 
     9/01/30 – MBIA Insured             
2,900    E-470 Public Highway Authority, Colorado, Toll Revenue Bonds, Series 2004A, 0.000%, 9/01/34 –    No Opt. Call    AAA    635,970 
     MBIA Insured             

15,400    Total Colorado            11,767,674 

    District of Columbia – 0.2% (0.1% of Total Investments)             
665    Washington Convention Center Authority, District of Columbia, Senior Lien Dedicated Tax    10/16 at 100.00    AAA    544,682 
     Revenue Bonds, Series 2007, Residuals 1606, 7.094%, 10/01/30 – AMBAC Insured (IF)             

    Florida – 1.2% (0.8% of Total Investments)             
3,000    Pinellas County Health Facilities Authority, Florida, Revenue Bonds, Baycare Health System,    5/13 at 100.00    Aa3 (4)    3,405,420 
     Series 2003, 5.500%, 11/15/27 (Pre-refunded 5/15/13)             

    Georgia – 2.1% (1.4% of Total Investments)             
1,410    DeKalb County, Georgia, Water and Sewer Revenue Bonds, Series 2006A, 5.000%, 10/01/35 –    10/16 at 100.00    AAA    1,470,842 
     FSA Insured             
3,825    Metropolitan Atlanta Rapid Transit Authority, Georgia, Sales Tax Revenue Bonds, Second    1/13 at 100.00    AAA    4,228,385 
     Indenture Series 2002, 5.000%, 7/01/32 (Pre-refunded 1/01/13) – MBIA Insured             

5,235    Total Georgia            5,699,227 

    Illinois – 3.7% (2.5% of Total Investments)             
905    Cook County School District 100, Berwyn South, Illinois, General Obligation Refunding Bonds,    12/13 at 100.00    Aaa    1,027,021 
     Series 2003B, 5.250%, 12/01/21 (Pre-refunded 12/01/13) – FSA Insured             
    Cook County School District 145, Arbor Park, Illinois, General Obligation Bonds, Series 2004:             
3,285     5.125%, 12/01/20 – FSA Insured    12/14 at 100.00    Aaa    3,552,432 
2,940     5.125%, 12/01/23 – FSA Insured    12/14 at 100.00    Aaa    3,131,717 
2,500    Illinois Health Facilities Authority, Revenue Bonds, Lake Forest Hospital, Series 2003,    7/13 at 100.00    A–    2,575,825 
     5.250%, 7/01/23             

9,630    Total Illinois            10,286,995 

    Indiana – 9.8% (6.4% of Total Investments)             
2,500    Evansville, Indiana, Sewerage Works Revenue Refunding Bonds, Series 2003A, 5.000%, 7/01/23 –    7/13 at 100.00    AAA    2,609,075 
     AMBAC Insured             
2,190    Indiana Bond Bank, Advance Purchase Funding Bonds, Common School Fund, Series 2003B, 5.000%,    8/13 at 100.00    AAA    2,323,021 
     8/01/19 – MBIA Insured             
1,860    Indiana Municipal Power Agency, Power Supply Revenue Bonds, Series 2007A, 5.000%, 1/01/42 –    1/17 at 100.00    AAA    1,879,251 
     MBIA Insured             
1,000    Indiana University, Student Fee Revenue Bonds, Series 2003O, 5.000%, 8/01/22 – FGIC Insured    8/13 at 100.00    Aaa    1,045,170 
    IPS Multi-School Building Corporation, Indiana, First Mortgage Revenue Bonds, Series 2003:             
11,020     5.000%, 7/15/19 (Pre-refunded 7/15/13) – MBIA Insured    7/13 at 100.00    AAA    12,282,231 
6,000     5.000%, 7/15/20 (Pre-refunded 7/15/13) – MBIA Insured    7/13 at 100.00    AAA    6,687,240 

24,570    Total Indiana            26,825,988 

    Kansas – 2.4% (1.6% of Total Investments)             
6,250    Kansas Development Finance Authority, Board of Regents, Revenue Bonds, Scientific Research and    4/13 at 102.00    AAA    6,583,563 
     Development Facilities Projects, Series 2003C, 5.000%, 10/01/22 – AMBAC Insured             

    Kentucky – 0.4% (0.3% of Total Investments)             
985    Kentucky State Property and Buildings Commission, Revenue Refunding Bonds, Project 77, Series    8/13 at 100.00    AAA    1,098,630 
     2003, 5.000%, 8/01/23 (Pre-refunded 8/01/13) – MBIA Insured             

    Louisiana – 2.2% (1.4% of Total Investments)             
5,785    New Orleans, Louisiana, General Obligation Refunding Bonds, Series 2002, 5.300%, 12/01/27 –    12/12 at 100.00    Aaa    6,015,995 
     FGIC Insured             

    Massachusetts – 4.0% (2.7% of Total Investments)             
9,000    Massachusetts Bay Transportation Authority, Senior Sales Tax Revenue Refunding Bonds, Series    7/12 at 100.00    AAA    9,881,820 
     2002A, 5.000%, 7/01/27 (Pre-refunded 7/01/12) – FGIC Insured             
1,125    Massachusetts Development Finance Authority, Revenue Bonds, Middlesex School, Series 2003,    9/13 at 100.00    A1    1,170,878 
     5.125%, 9/01/23             

10,125    Total Massachusetts            11,052,698 

    Michigan – 11.8% (7.8% of Total Investments)             
6,130    Detroit, Michigan, Senior Lien Water Supply System Revenue Bonds, Series 2003A, 5.000%,    7/13 at 100.00    AAA    6,827,717 
     7/01/23 (Pre-refunded 7/01/13) – MBIA Insured             
4,465    Detroit, Michigan, Senior Lien Water Supply System Revenue Refunding Bonds, Series 2003C,    7/13 at 100.00    AAA    4,689,679 
     5.000%, 7/01/22 – MBIA Insured             
1,000    Michigan State Hospital Finance Authority, Revenue Bonds, Trinity Health Care Group, Series    12/16 at 100.00    AA    1,005,250 
     2006A, 5.000%, 12/01/31             
10,800    Michigan Strategic Fund, Limited Obligation Resource Recovery Revenue Refunding Bonds, Detroit    12/12 at 100.00    AAA    10,963,728 
     Edison Company, Series 2002D, 5.250%, 12/15/32 – XLCA Insured             
2,250    Romulus Community Schools, Wayne County, Michigan, General Obligation Refunding Bonds, Series    5/11 at 100.00    AA-    2,359,260 
     2001, 5.250%, 5/01/25             
6,500    Wayne County, Michigan, Limited Tax General Obligation Airport Hotel Revenue Bonds, Detroit    12/11 at 101.00    AAA    6,630,910 
     Metropolitan Wayne County Airport, Series 2001A, 5.000%, 12/01/30 – MBIA Insured             

31,145    Total Michigan            32,476,544 

    Missouri – 1.1% (0.8% of Total Investments)             
240    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    260,702 
     2004, 5.250%, 3/01/24 – FSA Insured             
215    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    234,490 
     2004, 5.250%, 3/01/23 – FSA Insured             
    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds,             
    Series 2004:             
1,110     5.250%, 3/01/23 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,256,342 
1,260     5.250%, 3/01/24 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,426,118 

2,825    Total Missouri            3,177,652 

    Nebraska – 1.9% (1.2% of Total Investments)             
5,000    Lincoln, Nebraska, Sanitary Sewerage System Revenue Refunding Bonds, Series 2003, 5.000%,    6/13 at 100.00    AAA    5,117,850 
     6/15/28 – MBIA Insured             

    New Mexico – 0.8% (0.5% of Total Investments)             
1,975    New Mexico State University, Revenue Bonds, Series 2004, 5.000%, 4/01/19 – AMBAC Insured    4/14 at 100.00    AAA    2,107,681 

    New York – 10.6% (7.0% of Total Investments)             
20    Hudson Yards Infrastructure Corporation, New York, Revenue Bonds, Driver Trust 1649, 2006,    2/17 at 100.00    AAA    17,295 
     6.915%, 2/15/47 – MBIA Insured (IF)             
1,960    Hudson Yards Infrastructure Corporation, New York, Revenue Bonds, Series 2006A, 4.500%,    2/17 at 100.00    AAA    1,871,643 
     2/15/47 – MBIA Insured (UB)             
25,000    Metropolitan Transportation Authority, New York, Transportation Revenue Refunding Bonds,    11/12 at 100.00    AAA    25,434,500 
     Series 2002F, 5.000%, 11/15/31 – MBIA Insured             
1,850    New York State Urban Development Corporation, Service Contract Revenue Bonds, Series 2005B,    3/15 at 100.00    AAA    1,953,619 
     5.000%, 3/15/25 – FSA Insured             

28,830    Total New York            29,277,057 

    North Carolina – 3.2% (2.1% of Total Investments)             
8,700    North Carolina Medical Care Commission, Revenue Bonds, Maria Parham Medical Center, Series    10/13 at 100.00    AA    8,777,517 
     2003, 5.375%, 10/01/33 – RAAI Insured             

    Ohio – 1.1% (0.7% of Total Investments)             
    Buckeye Tobacco Settlement Financing Authority, Ohio, Tobacco Settlement Asset-Backed Revenue             
    Bonds, Senior Lien, Series 2007A-2:             
70     5.125%, 6/01/24    6/17 at 100.00    BBB    67,738 
710     5.875%, 6/01/30    6/17 at 100.00    BBB    706,436 
685     5.750%, 6/01/34    6/17 at 100.00    BBB    660,217 
1,570     5.875%, 6/01/47    6/17 at 100.00    BBB    1,516,259 

3,035    Total Ohio            2,950,650 

    Oklahoma – 0.4% (0.3% of Total Investments)             
1,000    Oklahoma Capitol Improvement Authority, State Facilities Revenue Bonds, Series 2005F, 5.000%,    7/15 at 100.00    AAA    1,050,170 
     7/01/24 – AMBAC Insured             

    Oregon – 3.1% (2.0% of Total Investments)             
8,350    Oregon Health Sciences University, Revenue Bonds, Series 2002A, 5.000%, 7/01/32 – MBIA Insured    1/13 at 100.00    AAA    8,495,123 

    Pennsylvania – 7.6% (5.0% of Total Investments)             
3,000    Lehigh County General Purpose Authority, Pennsylvania, Hospital Revenue Bonds, St. Luke’s    8/13 at 100.00    Baa1 (4)    3,382,770 
     Hospital of Bethlehem, Series 2003, 5.375%, 8/15/33 (Pre-refunded 8/15/13)             
2,000    Philadelphia Gas Works, Pennsylvania, Revenue Bonds, General Ordinance, Fourth Series 1998,    8/13 at 100.00    AAA    2,052,660 
     5.000%, 8/01/32 – FSA Insured             
925    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%,    2/08 at 102.00    AAA    941,724 
     8/01/27 – AMBAC Insured (ETM)             
13,000    State Public School Building Authority, Pennsylvania, Lease Revenue Bonds, Philadelphia School    6/13 at 100.00    AAA    14,461,720 
     District, Series 2003, 5.000%, 6/01/33 (Pre-refunded 6/01/13) – FSA Insured             

18,925    Total Pennsylvania            20,838,874 

    Puerto Rico – 0.5% (0.4% of Total Investments)             
10,000    Puerto Rico Sales Tax Financing Corporation, Sales Tax Revenue Bonds, Series 2007A, 0.000%,    No Opt. Call    AAA    1,513,600 
     8/01/43 – MBIA Insured             

    South Carolina – 7.2% (4.8% of Total Investments)             
5,000    Florence County, South Carolina, Hospital Revenue Bonds, McLeod Regional Medical Center,    11/14 at 100.00    AAA    5,282,900 
     Series 2004A, 5.250%, 11/01/23 – FSA Insured             
    Greenville County School District, South Carolina, Installment Purchase Revenue Bonds,             
    Series 2003:             
3,000     5.000%, 12/01/22    12/13 at 100.00    AA–    3,117,360 
1,785     5.000%, 12/01/23    12/13 at 100.00    AA–    1,848,296 
1,365    Myrtle Beach, South Carolina, Water and Sewerage System Revenue Refunding Bonds, Series 2003,    3/13 at 100.00    Aaa    1,536,976 
     5.375%, 3/01/19 (Pre-refunded 3/01/13) – FGIC Insured             
8,000    South Carolina Transportation Infrastructure Bank, Revenue Bonds, Series 2002A, 5.000%,    10/12 at 100.00    Aaa    8,129,200 
     10/01/33 – AMBAC Insured             

19,150    Total South Carolina            19,914,732 

    Texas – 13.3% (8.8% of Total Investments)             
7,975    Fort Bend Independent School District, Fort Bend County, Texas, General Obligation Bonds,    8/10 at 100.00    AAA    8,259,149 
     Series 2000, 5.000%, 8/15/25             
12,500    Grand Prairie Independent School District, Dallas County, Texas, General Obligation Bonds,    2/13 at 100.00    AAA    13,917,750 
     Series 2003, 5.125%, 2/15/31 (Pre-refunded 2/15/13) – FSA Insured             
2,000    Houston, Texas, First Lien Combined Utility System Revenue Bonds, Series 2004A, 5.250%,    5/14 at 100.00    AAA    2,088,460 
     5/15/25 – MBIA Insured             
5,515    Houston, Texas, General Obligation Refunding Bonds, Series 2002, 5.250%, 3/01/20 – MBIA Insured    3/12 at 100.00    AAA    5,884,505 
5,850    Katy Independent School District, Harris, Fort Bend and Waller Counties, Texas, General    2/12 at 100.00    AAA    6,346,373 
     Obligation Bonds, Series 2002A, 5.125%, 2/15/18             

33,840    Total Texas            36,496,237 

    Virginia – 0.6% (0.4% of Total Investments)             
1,500    Hampton, Virginia, Revenue Bonds, Convention Center Project, Series 2002, 5.125%, 1/15/28 –    1/13 at 100.00    AAA    1,535,115 
     AMBAC Insured             

    Washington – 9.1% (6.0% of Total Investments)             
4,945    Broadway Office Properties, King County, Washington, Lease Revenue Bonds, Washington Project,    12/12 at 100.00    AAA    5,019,917 
     Series 2002, 5.000%, 12/01/31 – MBIA Insured             
5,250    Chelan County Public Utility District 1, Washington, Hydro Consolidated System Revenue Bonds,    7/12 at 100.00    AAA    5,354,423 
     Series 2002C, 5.125%, 7/01/33 – AMBAC Insured             
2,135    Kitsap County Consolidated Housing Authority, Washington, Revenue Bonds, Bremerton Government    7/13 at 100.00    Aaa    2,210,109 
     Center, Series 2003, 5.000%, 7/01/23 – MBIA Insured             
1,935    Pierce County School District 343, Dieringer, Washington, General Obligation Refunding Bonds,    6/13 at 100.00    Aaa    2,124,804 
     Series 2003, 5.250%, 12/01/17 – FGIC Insured             
9,670    Washington State, General Obligation Bonds, Series 2003D, 5.000%, 12/01/21 – MBIA Insured    6/13 at 100.00    AAA    10,172,453 

23,935    Total Washington            24,881,706 

    West Virginia – 1.2% (0.8% of Total Investments)             
3,000    West Virginia State Building Commission, Lease Revenue Refunding Bonds, Regional Jail and    No Opt. Call    AAA    3,384,990 
     Corrections Facility, Series 1998A, 5.375%, 7/01/21 – AMBAC Insured             

    Wisconsin – 6.7% (4.4% of Total Investments)             
1,190    Sun Prairie Area School District, Dane County, Wisconsin, General Obligation Bonds, Series    3/14 at 100.00    Aaa    1,315,188 
     2004C, 5.250%, 3/01/24 – FSA Insured             
4,605    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Franciscan Sisters of    9/13 at 100.00    BBB+ (4)    5,314,584 
     Christian Charity Healthcare Ministry, Series 2003A, 5.875%, 9/01/33 (Pre-refunded 9/01/13)             
3,000    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Meriter Hospital Inc.,    No Opt. Call    Aaa    3,508,260 
     Series 1992A, 6.000%, 12/01/22 – FGIC Insured             
3,600    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Wheaton Franciscan    8/13 at 100.00    A–    3,289,392 
     Services Inc., Series 2003A, 5.125%, 8/15/33             
4,750    Wisconsin Health and Educational Facilities Authority, Revenue Refunding Bonds, Wausau    8/08 at 102.00    AAA    4,890,125 
     Hospital Inc., Series 1998A, 5.125%, 8/15/20 – AMBAC Insured             

17,145    Total Wisconsin            18,317,549 

$      408,740    Total Investments (cost $395,753,007) – 151.4%            415,942,160 


    Floating Rate Obligations – (0.5)%            (1,305,000)

    Other Assets Less Liabilities – 1.5%            4,023,486 

    Preferred Shares, at Liquidation Value – (52.4)% (5)            (144,000,000)

    Net Assets Applicable to Common Shares – 100%          $  274,660,646 



    At least 80% of the Fund’s net assets (including net assets attributable to Preferred shares) are invested 
    in municipal securities that are either covered by Original Issue Insurance, Secondary Market Insurance or 
    Portfolio Insurance which ensures the timely payment of principal and interest. Up to 20% of the Fund’s 
    net assets (including net assets attributable to Preferred shares) may be invested in municipal securities 
    that are (i) either backed by an escrow or trust containing sufficient U.S. Government or U.S. Government 
    agency securities (also ensuring the timely payment of principal and interest), or (ii) rated, at the time of 
    investment, within the four highest grades (Baa or BBB or better by Moody’s, Standard & Poor's or Fitch) 
    or unrated but judged to be of comparable quality by the Adviser. 
    The Fund may invest in “zero coupon” securities. A zero coupon security does not pay a regular interest 
    coupon to its holders during the life of the security. Tax-exempt income to the holder of the security comes 
    from accretion of the difference between the original purchase price of the security at issuance and the 
    par value of the security at maturity and is effectively paid at maturity. Such securities are included in the 
    Portfolio of Investments with a 0.000% coupon rate in their description. The market prices of zero coupon 
    securities generally are more volatile than the market prices of securities that pay interest periodically. 
(1)    All percentages shown in the Portfolio of Investments are based on net assets applicable to Common 
    shares unless otherwise noted. 
(2)    Optional Call Provisions: Dates (month and year) and prices of the earliest optional call or redemption. 
    There may be other call provisions at varying prices at later dates. Certain mortgage-backed securities 
    may be subject to periodic principal paydowns. 
(3)    Ratings: Using the higher of Standard & Poor's Group ("Standard & Poor's") or Moody's Investor Service, 
    Inc. ("Moody's") rating. Ratings below BBB by Standard & Poor's or Baa by Moody's are considered to be 
    below investment grade. 
    The AAA ratings shown in the Portfolio of Investments reflect the AAA ratings on certain bonds that may 
    be insured by AMBAC, FGIC, XLCA or MBIA as of January 31, 2008. Subsequent to January 31, 2008, at 
    least one rating agency reduced the rating for AMBAC-insured bonds to AA and XLCA-insured and 
    FGIC-insured bonds experienced further downgrades such that they no longer carry AAA ratings which 
    had the effect of reducing the rating of many (if not all) of the bonds insured by those particular insurers. 
    One or more rating agencies have placed each of these insurers on “negative credit watch”, which may 
    presage one or more rating reductions for such insurer or insurers in the future. If one or more insurers’ 
    ratings are reduced below AAA by these rating agencies, it would likely reduce the effective rating of 
    many of the bonds insured by that insurer or insurers. 
(4)    Backed by an escrow or trust containing sufficient U.S. Government or U.S. Government agency securities 
    which ensure the timely payment of principal and interest. Such investments are normally considered to 
    be equivalent to AAA rated securities. 
(5)    Preferred Shares, at Liquidation Value as a percentage of total investments is (34.6)%. 
(ETM)    Escrowed to maturity. 
(IF)    Inverse floating rate investment. 
(UB)    Underlying bond of an inverse floating rate trust reflected as a financing transaction pursuant to the 
    provisions of SFAS No. 140. 

Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to the treatment of paydown gains and losses, timing differences in recognizing taxable market discount, timing differences in recognizing certain gains and losses on investment transactions and the treatment of investments in inverse floating rate transactions subject to SFAS No.140. To the extent that differences arise that are permanent in nature, such amounts are reclassified within the capital accounts on the Statement of Assets and Liabilities presented in the annual report, based on their federal tax basis treatment; temporary differences do not require reclassification. Temporary and permanent differences do not impact the net asset value of the Fund.

At January 31, 2008, the cost of investments was $394,394,772.

Gross unrealized appreciation and gross unrealized depreciation of investments at January 31, 2008, were as follows:


Gross unrealized:     
  Appreciation    $21,587,388 
  Depreciation    (1,345,225) 

Net unrealized appreciation (depreciation) of investments    $20,242,163 



Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: EX-99 CERT Attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Insured Tax-Free Advantage Municipal Fund         

By (Signature and Title)*          /s/ Kevin J. McCarthy                    
                                                    Kevin J. McCarthy
                                                    Vice President and Secretary

Date         March 31, 2008        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)*         /s/ Gifford R. Zimmerman                    
                                                   Gifford R. Zimmerman
                                                   Chief Administrative Officer (principal executive officer) 

Date         March 31, 2008        

By (Signature and Title)*         /s/ Stephen D. Foy                              
                                                   Stephen D. Foy
                                                   Vice President and Controller (principal financial officer) 

Date        March 31, 2008        

* Print the name and title of each signing officer under his or her signature.