Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Grigoriadis Dimitri E.
 2. Date of Event Requiring Statement (Month/Day/Year)
01/10/2008		 3. Issuer Name and Ticker or Trading Symbol
NEUROCRINE BIOSCIENCES INC [NBIX]
(Last)
(First)
(Middle)
NEUROCRINE BIOSCIENCES, INC., 12790 EL CAMINO REAL		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Vice President, Research
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN DIEGO, CA 92130		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 4,358
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (right to buy) (1) 09/19/1998 08/19/2008 Common Stock 7,500 $ 6.5 D  
Employee Stock Option (right to buy) (2) 07/01/1999 06/01/2009 Common Stock 4,000 $ 4.875 D  
Employee Stock Option (right to buy) (3) 09/26/2007 07/23/2013 Common Stock 937 $ 10.9 D  
Employee Stock Option (right to buy) (3) 09/26/2007 09/26/2013 Common Stock 4,737 $ 10.9 D  
Employee Stock Option (right to buy) (3) 09/26/2007 06/22/2010 Common Stock 3,750 $ 10.9 D  
Employee Stock Option (right to buy) (3) 09/26/2007 06/26/2011 Common Stock 3,125 $ 10.9 D  
Employee Stock Option (right to buy) (3) 09/26/2007 07/05/2012 Common Stock 3,250 $ 10.9 D  
Employee Stock Option (right to buy) (3) 09/26/2007 09/05/2012 Common Stock 10,125 $ 10.9 D  
Restricted Stock Units   (4)   (4) Common Stock 16,667 $ (5) D  
Restricted Stock Units   (6)   (6) Common Stock 10,000 $ (5) D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Grigoriadis Dimitri E.
NEUROCRINE BIOSCIENCES, INC.
12790 EL CAMINO REAL
SAN DIEGO, CA 92130		       Vice President, Research  

Signatures

Margaret E. Valeur-Jensen, By Power of Attorney 01/17/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Represents option of which one forty-eighth (1/48) of the shares underlying the option becomes vested and exercisable on September 19, 1998 and an additional one forty-eighth (1/48) of the shares underlying the option becomes vested and exercisable each month thereafter.
(2) Represents option of which one forty-eighth (1/48) of the shares underlying the option becomes vested and exercisable on July 1, 1999 and an additional one forty-eighth (1/48) of the shares underlying the option becomes vested and exercisable each month thereafter.
(3) This option is exercisable in three annual installments. The first installment became exercisable on September 26, 2007, and the next two installments become exercisable on September 26, 2008 and September 26, 2009.
(4) The restricted stock units vest in three annual installments. The first installment became exercisable on October 26, 2007, and the next two installments become exercisable on September 26, 2008 and September 26, 2009.
(5) Each restricted stock unit represents a contingent right to receive one share of NBIX common stock.
(6) The restricted stock units vest in three annual installments beginning February 3, 2008 and the next two installments become exercisable on January 3, 2009 and January 3, 2010.

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