Filed by Exelixis, Inc.
                       Pursuant to Rule 425 under the Securities Act of 1933 and
            Deemed filed under Rule 14d-2 of the Securities Exchange Act of 1934

                                           Subject Company: Genomica Corporation

                                                  Commission File No.: 000-31637




                             SOURCE: EXELIXIS, INC.

                          Wednesday December 26, 2001

                                  Press Release

Contact:
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Exelixis, Inc.                                   Genomica Corporation
Glen Sato                                        Dan Hudspeth
Chief Financial Officer                          Chief Financial Officer
(650)837-7565                                    (720) 565-4030

                  EXELIXIS AND GENOMICA ANNOUNCE EXCHANGE RATIO

    - Each outstanding share of Genomica Common Stock Subject to Exchange for
                    0.28306 shares of Exelixis Common Stock -

SOUTH  SAN  FRANCISCO,  CA -- December 26, 2001 -- Exelixis, Inc. (Nasdaq: EXEL)
and  Genomica Corporation (Nasdaq: GNOM) announced today that the exchange ratio
of shares of Genomica common stock into shares of Exelixis common stock shall be
0.28306.  The  initial  offering  period for the exchange offer made by Exelixis
for  shares  of common stock of Genomica will expire at 12:00 midnight, New York
City  time,  on  Friday,  December 28, 2001.  The exchange offer, if successful,
will  be  followed  by  a  merger  in  which  Exelixis will acquire, at the same
exchange  ratio,  the  remaining  shares of Genomica common stock not previously
acquired  in  the  exchange  offer.

The  exchange  ratio of Exelixis common stock for outstanding shares of Genomica
common  stock was determined by the following formula:  (a) $110 million divided
by  24,463,141  (which  represents  the  sum of the number of shares of Genomica
common  stock  and  preferred  stock  outstanding  plus  the number of shares of
Genomica  common  stock  issuable  upon  the  exercise  of all outstanding stock
options  and  warrants with a per share exercise price of $5.00 or less) divided
by  (b)  $15.88556  (which is the average closing sales price of Exelixis common
stock  on  the  Nasdaq  National  Market  for  the  18 trading-day period ending
December  26,  2001).

The  Genomica  Corporation  board  of directors has unanimously recommended that
Genomica  stockholders  accept  the  exchange  offer.  Genomica stockholders are
urged  to  carefully  read  the  Preliminary  Prospectus  and  the
Solicitation/Recommendation  statement previously filed with the SEC and any and
all  amendments  thereto.

ABOUT  EXELIXIS
Exelixis,  Inc.  is  a  leading  worldwide genomics-based drug discovery company
focused on product development through its expertise in comparative genomics and
model  system genetics.  An outstanding team of company scientists has developed
multiple  fungal,  nematode,  insect,  plant  and  vertebrate  genetic  systems.
Exelixis'  proprietary  model  systems  and  comparative  genomics  technologies
address  gene  function  by  using  biologically  relevant  functional  genomics
information  very  early  on  in  the  process  to  rapidly,  efficiently  and
cost-effectively  translate  sequence  data  to  knowledge about the function of
genes and the proteins that they encode.  The company has a significant internal
cancer  discovery  and  drug  development  program,  through  which  a number of
compounds  are  expected to complete screening by the end of the year.  Exelixis
believes  that  its  technology  is  broadly  applicable  to  all  life  science
industries, including pharmaceutical, diagnostic, agricultural biotechnology and
animal  health  and  the  company  has  active  collaborations  with  Aventis
CropScience,  Bayer,  Bristol-Myers  Squibb,  Elan  Pharmaceuticals,  Pharmacia,
Protein  Design  Labs,  Scios and Dow AgroSciences, and is building its internal
development program in the area of oncology.  For more information, please visit
the  Exelixis'  web  site  at  http://www.Exelixis.com/.
                               ------------------------

ABOUT  GENOMICA
Genomica  Corporation  develops  and markets software products and services that
enable  pharmaceutical  and  biotechnology  researchers  to  accelerate the drug
discovery  and  development  process.  Genomica's  customers  include  leading
genomics-based  research  organizations  such  as  AstraZeneca, GlaxoSmithKline,
Aventis  and  the  National  Cancer  Institute.  Genomica  also  has  strategic
alliances  with  Applied  Biosystems  and  Celera  Genomics.  For  additional
information  on  Genomica, please visit its website, at http://www.Genomica.com.
                                                        -----------------------

ADDITIONAL  INFORMATION
Exelixis  has  filed a Schedule TO and a Registration Statement on Form S-4, and
Genomica  has  filed  a  Solicitation/Recommendation Statement on Schedule 14D-9
with  the  Securities  and  Exchange  Commission.  A Preliminary Prospectus, the
Schedule 14D-9 and related tender offer materials were mailed to stockholders of
Genomica  on  November  29, 2001.  These documents contain important information
about  the  transaction.  Investors  and security holders are urged to carefully
read  these  documents,  and  any  and  all  amendments  thereto.  Investors and
security  holders  will be able to obtain free copies of these documents through
the  website  maintained  by  the  U.S.  Securities  and  Exchange Commission at
http://www.sec.gov.  The  Preliminary  Prospectus and related other tender offer
documents  may  also  be  obtained  for  free  from  the  parties.

In  addition  to the filings mentioned above, each of Exelixis and Genomica file
annual,  quarterly  and  special reports, proxy statements and other information
with the Securities and Exchange Commission.  You may read and copy any reports,
statements  or other information filed by Exelixis or Genomica at the SEC public
reference  room  at  450 Fifth Street, N.W., Washington, D.C. 20549 or at any of
the  Commission's  other  public  reference rooms in New York, N.Y. and Chicago,
Ill.  Please  call  the  Securities  and Exchange Commission at 800-SEC-0330 for
further  information  on  the  public  reference rooms.  Exelixis and Genomica's
respective  filings  with  the  Securities  and  Exchange  Commission  are  also
available  to  the public from commercial document-retrieval services and at the
website  maintained  by  the  commission  at  http://www.sec.gov.
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