SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                 Schedule 13G/A


 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1 (b), (c)
           AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 (b)
                               (Amendment No. 1)*


                                  Aerogen, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    007779309
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                                December 31, 2004
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

             [ ]    Rule 13d-1(b)

             [ ]    Rule 13d-1(c)

             [X]    Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                         (Continued on following pages)



                               Page 1 of 12 Pages







                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 2 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      U.S. Venture Partners IV, L.P. ("USVP IV")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       307,959 shares, except that Presidio Management Group IV, L.P.
           OWNED BY EACH                      ("PMG IV"), the general partner of USVP IV, may be deemed to have sole
             REPORTING                        voting power with respect to such shares, and William K Bowes, Jr.
              PERSON                          ("Bowes"), Irwin Federman ("Federman"), Steven M. Krausz ("Krausz")
               WITH                           and Philip M. Young ("Young"), the general partners of PMG IV, may be
                                              deemed to have shared voting power with respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     6        SHARED VOTING POWER
                                              See response to row 5.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              307,959 shares, except that PMG IV, the general partner of USVP IV,
                                              may be deemed to have sole dispositive power with respect to such
                                              shares, and Bowes, Federman, Krausz and Young, the general partners of
                                              PMG IV, may be deemed to have shared dispositive power with respect to
                                              such shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------ ---------------------------------------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       307,959
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      PN
------------ ---------------------------------------------------------------------------------------------------------

                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!








                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 3 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      Second Ventures II, L.P. ("SV II")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Cayman Islands
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       37,386 shares, except that PMG IV, the general partner of SV II, may
           OWNED BY EACH                      be deemed to have sole voting power with respect to such shares, and
             REPORTING                        Bowes, Federman, Krausz and Young, the general partners of PMG IV, may
              PERSON                          be deemed to have shared voting power with respect to such shares.
               WITH                  -------- ------------------------------------------------------------------------

                                     6        SHARED VOTING POWER
                                              See response to row 5.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              37,386 shares, except that PMG IV, the general partner of SV II, may
                                              be deemed to have sole dispositive power with respect to such shares,
                                              and Bowes, Federman, Krausz and Young, the general partners of PMG IV,
                                              may be deemed to have shared dispositive power with respect to such
                                              shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------ ---------------------------------------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       37,386
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    0.8 %
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      PN
------------ ---------------------------------------------------------------------------------------------------------


                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!







                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 4 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      USVP Entrepreneur Partners II, L.P. ("UEP II")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------------------------------ -------- ------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       10,684 shares, except that PMG IV, the general partner of UEP II, may
           OWNED BY EACH                      be deemed to have sole voting power with respect to such shares, and
             REPORTING                        Bowes, Federman, Krausz and Young, the general partners  of PMG IV, may
              PERSON                          be deemed to have shared voting power with respect to such shares.
               WITH                  -------- ------------------------------------------------------------------------

                                     6        SHARED VOTING POWER
                                              See response to row 5.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              10,684 shares, except that PMG IV, the general partner of UEP II, may
                                              be deemed to have sole dispositive power with respect to such shares,
                                              and Bowes, Federman, Krausz and Young, the general partners of PMG IV,
                                              may be deemed to have shared dispositive power with respect to such
                                              shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------------------------------ -------- ------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       10,684
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    0.2%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      PN
------------ ---------------------------------------------------------------------------------------------------------


                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!







                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 5 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      Presidio Management Group IV, L.P. ("PMG IV")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF                        SOLE VOTING POWER
              SHARES                 5        356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
           BENEFICIALLY                       are directly owned by SV II and 10,684 are directly owned by UEP II.
           OWNED BY EACH                      PMG IV is the general partner of USVP IV, SV II and UEP II, and may be
             REPORTING                        deemed to have sole voting power with respect to such shares, and
              PERSON                          Bowes, Federman, Krausz and Young, the general partners of PMG IV, may
               WITH                           be deemed to have shared voting power with respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     6        See response to row 5.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              PMG IV is the general partner of USVP IV, SV II and UEP II, and may be
                                              deemed to have sole dispositive power with respect to such shares, and
                                              Bowes, Federman, Krausz and Young, the general partners of PMG IV, may
                                              be deemed to have shared dispositive power with respect to such
                                              shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------------------------------ -------- ------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       356,029
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    7.3%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      PN
------------ ---------------------------------------------------------------------------------------------------------


                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!






                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 6 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.    IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                       William K. Bowes, Jr. ("Bowes")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH             -------- ------------------------------------------------------------------------
             REPORTING
              PERSON                 6        SHARED VOTING POWER
               WITH                           356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Bowes is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared voting power with
                                              respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Bowes is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared dispositive power
                                              with respect to such shares.
------------ ---------------------------------------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       356,029
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    7.3%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      IN
------------ ---------------------------------------------------------------------------------------------------------


                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!






                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 7 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      Irwin Federman ("Federman")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH             -------- ------------------------------------------------------------------------
             REPORTING
              PERSON                 6        SHARED VOTING POWER
               WITH                           356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Federman is a general partner of PMG IV, the general partner of USVP
                                              IV, SV II and UEP II, and may be deemed to have shared voting power
                                              with respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER

                                              356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Federman is a general partner of PMG IV, the general partner of USVP
                                              IV, SV II and UEP II, and may be deemed to have shared dispositive
                                              power with respect to such shares.
------------------------------------ -------- ------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       356,029
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    7.3%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      IN
------------ ---------------------------------------------------------------------------------------------------------


                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!








                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 8 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      Steven M. Krausz ("Krausz")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH             -------- ------------------------------------------------------------------------
             REPORTING
              PERSON                 6        SHARED VOTING POWER
               WITH                           356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Krausz is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared voting power with
                                              respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Krausz is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared dispositive power
                                              with respect to such shares.
------------------------------------ -------- ------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       356,029
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    7.3%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      IN
------------ ---------------------------------------------------------------------------------------------------------


                                                 *SEE INSTRUCTIONS BEFORE FILLING OUT!








                                  
----------------------------------------------------------                     --------------------------------------
CUSIP NO. 007779101                                               13 G                  Page 9 of 12 Pages
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------

1            NAME OF REPORTING PERSON
             I.R.S.   IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
                      Philip M. Young ("Young")
------------ ---------------------------------------------------------------------------------------------------------

2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                (a)   [ ]           (b)   [X]
------------ ---------------------------------------------------------------------------------------------------------

3            SEC USE ONLY
------------ ---------------------------------------------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------
             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       15,194 shares.
           OWNED BY EACH             -------- ------------------------------------------------------------------------
             REPORTING
              PERSON                 6        SHARED VOTING POWER
               WITH                           356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Young is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared voting power with
                                              respect to such shares.
                                     -------- ------------------------------------------------------------------------

                                     7        SOLE DISPOSITIVE POWER
                                              15,194 shares.
                                     -------- ------------------------------------------------------------------------

                                     8        SHARED DISPOSITIVE POWER
                                              356,029 shares, of which 307,959 are directly owned by USVP IV, 37,386
                                              are directly owned by SV II and 10,684 are directly owned by UEP II.
                                              Young is a general partner of PMG IV, the general partner of USVP IV,
                                              SV II and UEP II, and may be deemed to have shared dispositive power
                                              with respect to such shares.
------------------------------------ -------- ------------------------------------------------------------------------

9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       371,223
------------ ---------------------------------------------------------------------------------------------------------

10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES*                                                               [ ]
------------ ---------------------------------------------------------------------------------------------------------

11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                    7.6%
------------ ---------------------------------------------------------------------------------------------------------

12           TYPE OF REPORTING PERSON*
                                                                                                      IN
------------ ---------------------------------------------------------------------------------------------------------

                                       * SEE INSTRUCTIONS BEFORE FILLING OUT!






                                                             Page 10 of 12 Pages


         This Amendment No. 1 amends the previous statement on Schedule 13G
filed by U.S. Venture Partners IV, L.P., Second Ventures II, L.P., USVP
Entrepreneur Partners II, L.P., Presidio Management Group IV, L.P., William K.
Bowes, Jr., Irwin Federman, Steven M. Krausz and Philip M. Young. The foregoing
entities and individuals are collectively referred to as the "Reporting
Persons." Only those items as to which there has been a change are included in
this Amendment No. 1.



ITEM 4.           OWNERSHIP:

                  The following information with respect to the ownership of the
                  Common Stock of the issuer by the persons filing this
                  Statement is provided as of December 31, 2004:

                           (a) Amount beneficially owned:

                           See Row 9 of cover page for each Reporting Person.

                           (b) Percent of Class:

                           See Row 11 of cover page for each Reporting Person.

                           (c) Number of shares as to which such person has:

                               (i)   Sole power to vote or
                                     to direct the vote:

                                     See Row 5 of cover page for each
                                     Reporting Person.

                               (ii)  Shared power to vote or to direct the vote:

                                     See Row 6 of cover page for each
                                     Reporting Person.

                               (iii) Sole power to dispose
                                     or to direct the disposition of:

                                     See Row 7 of cover page for each
                                     Reporting Person.

                               (iv)  Shared power to dispose or to direct the
                                     disposition of:

                                     See Row 8 of cover page for each
                                     Reporting Person.





                                                             Page 11 of 12 Pages

                                   SIGNATURES


         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.


Dated:  February 10, 2005



                                                              
U.S. Venture Partners IV, L.P.                                   /s/ Michael Maher
By Presidio Management Group IV, L.P.                            --------------------------------------------------
Its General Partner                                              Signature

                                                                 Michael Maher
                                                                 Chief Financial Officer/Attorney-In-Fact


Second Ventures II, L.P.                                         /s/ Michael Maher
By Presidio Management Group IV, L.P.                            --------------------------------------------------
Its General Partner                                              Signature

                                                                 Michael Maher
                                                                 Chief Financial Officer/Attorney-In-Fact


USVP Entrepreneur Partners II, L.P.                              /s/ Michael Maher
By Presidio Management Group IV, L.P.                            --------------------------------------------------
Its General Partner                                              Signature

                                                                 Michael Maher
                                                                 Chief Financial Officer/Attorney-In-Fact


Presidio Management Group IV, L.P.                               /s/ Michael Maher
A Delaware Limited Partnership                                   --------------------------------------------------
                                                                 Signature

                                                                 Michael Maher
                                                                 Chief Financial Officer/Attorney-In-Fact


William K. Bowes, Jr.                                            /s/ Michael Maher
                                                                 --------------------------------------------------
                                                                 Michael Maher
                                                                 Attorney-In-Fact



                                                             Page 12 of 12 Pages



                                                              
Irwin Federman                                                   /s/ Michael Maher
                                                                 --------------------------------------------------
                                                                 Michael Maher
                                                                 Attorney-In-Fact


Steven M. Krausz                                                 /s/ Michael Maher
                                                                 --------------------------------------------------
                                                                 Michael Maher
                                                                 Attorney-In-Fact


Philip M. Young                                                  /s/ Michael Maher
                                                                 --------------------------------------------------
                                                                 Michael Maher
                                                                 Attorney-In-Fact