United States
                       Securities and Exchange Commission
                             WASHINGTON, D.C. 20549


                                  Schedule 13G
                              (Amendment No. _1_)*

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934


                                  CUTERA, INC.
                                  ------------
                                (Name of Issuer)

                                  Common Stock
                        ---------------------------------
                         (Title of Class of Securities)

                                    232109108
                        ---------------------------------
                                 (CUSIP Number)


                                February 22, 2005
--------------------------------------------------------------------------------
             (Date of Event That Requires Filing of this Statement)

Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

         |_|      Rule 13d-1(b)

         |X|      Rule 13d-1(c)

         |_|      Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



CUSIP No.  232109108                                          Page 2 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Alta Partners                                                          
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         California                                                             
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          -0-
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     -0-
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         -0-      Exit Filing -- Please see Attachment A                        
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.00%    Exit Filing -- Please see Attachment A        
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IA    
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



CUSIP No. 232109108                                           Page 3 of 16 Pages



--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Alta California Partners II, L. P.                                     
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         Delaware                                                               
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          -0-
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     -0-
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         -0-      Exit Filing -- Please see Attachment A              
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.00%    Exit Filing -- Please see Attachment A 
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  PN   
--------------------------------------------------------------------------------



CUSIP No. 232109108                                           Page 4 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Alta California Management Partners II, LLC  
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         Delaware         
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          -0-
Beneficially Owned
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     -0-
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         -0-      Exit Filing -- Please see Attachment A           
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.00%    Exit Filing -- Please see Attachment A        
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  CO
--------------------------------------------------------------------------------



CUSIP No. 232109108                                           Page 5 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Alta Embarcadero Partners II, LLC                  
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         California                                                     
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          -0-
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     -0-
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-      
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         -0-      Exit Filing -- Please see Attachment A    
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.00%    Exit Filing -- Please see Attachment A   
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  CO                                          
--------------------------------------------------------------------------------



CUSIP No. 232109108                                           Page 6 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Guy Nohra                                            
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         United States                                                   
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          31,737
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     31,737
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0- 
                                        Exit Filing -- Please see Attachment A 
                                        & Footnote 1
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         31,737   Exit Filing -- Please see Attachment A      
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.29 %   Exit Filing -- Please see Attachment A    
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IN                           
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



CUSIP No. 232109108                                           Page 7 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Jean Deleage 
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         United States                                      
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          1,913
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7       Sole Dispositive Power     1,913
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         1,913    Exit Filing -- Please see Attachment A                   
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.02%    Exit Filing -- Please see Attachment A            
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IN         
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



CUSIP No. 232109108                                           Page 8 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Garrett Gruener  
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         United States                                              
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          2,726
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     2,726
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         2,726    Exit Filing -- Please see Attachment A                  
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.03%    Exit Filing -- Please see Attachment A   
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IN                                                
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



CUSIP No. 232109108                                           Page 9 of 16 Pages

                                                              
--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Daniel Janney                                                
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         United States                                     
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          1,376
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     1,376
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         1,376    Exit Filing -- Please see Attachment A       
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.01 %   Exit Filing -- Please see Attachment A        
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IN   
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



CUSIP No. 232109108                                          Page 10 of 16 Pages


--------------------------------------------------------------------------------
  (1)    Names of Reporting Persons.  SS or I.R.S.  Identification Nos. of Above
         Persons

         Alix Marduel                                                           
--------------------------------------------------------------------------------
  (2)    Check The Appropriate Box If A Member Of A Group          (a)
                                                                   (b)  X
--------------------------------------------------------------------------------
  (3)    SEC Use Only

--------------------------------------------------------------------------------
  (4)    Citizenship or Place of Organization

         United States                                                          
--------------------------------------------------------------------------------
                     Exit Filing -- Please see Attachment A

Number Of Shares               (5)      Sole Voting Power          1,817
Beneficially Owned             -------------------------------------------------
By Each Reporting              (6)      Shared Voting Power        -0-
Person With                             Exit Filing -- Please see Attachment A
                               -------------------------------------------------
                               (7)      Sole Dispositive Power     1,817
                               -------------------------------------------------
                               (8)      Shared Dispositive Power   -0-
                                        Exit Filing -- Please see Attachment A
--------------------------------------------------------------------------------
  (9)    Aggregate Amount Beneficially Owned By Each Reporting Person

         1,817    Exit Filing -- Please see Attachment A                   
--------------------------------------------------------------------------------
  (10)   Check If The Aggregate Amount In Row (11) Excludes Certain Shares*

--------------------------------------------------------------------------------
  (11)   Percent Of Class Represented By Amount In Row (11)

         0.02 %   Exit Filing -- Please see Attachment A 
--------------------------------------------------------------------------------
  (12)   Type Of Reporting Person

                  IN  
--------------------------------------------------------------------------------
                      *SEE INSTRUCTION BEFORE FILLING OUT!



                                                             Page 11 of 16 Pages

Item 1.

(a) Name of Issuer: Cutera, Inc. ("Issuer")

(b) Address of Issuer's Principal Executive Offices:

                  3240 Bayshore Blvd.
                  Burlingame, CA 94005


Item 2.

(a) Name of Person Filing:

         Alta Partners ("AP")
         Alta California Partners II, L.P. ("ACPII") Alta California  Management
         Partners II, LLC ("ACMPII") Alta Embarcadero Partners II, LLC ("AEPII")
         Jean Deleage  ("JD")  Garrett  Gruener ("GG") Daniel Janney ("DJ") Alix
         Marduel ("AM") Guy Nohra ("GN")

 (b) Address of Principal Business Office:

         One Embarcadero Center, Suite 4050
         San Francisco, CA  94111

 (c) Citizenship/Place of Organization:


         Entities:         AP               California
                           ACPII            Delaware
                           ACMPII           Delaware
                           AEPII            California


         Individuals:      JD               United States
                           GG               United States
                           DJ               United States
                           AM               United States
                           GN               United States


(d) Title of Class of Securities: Common Stock

(e) CUSIP Number: 232109108

Item 3.  Not applicable.



                                                             Page 12 of 16 Pages


Item 4         Ownership.



                     Exit Filing -- Please see Attachment A
------- ------------------ ----------- ----------- ------------ ----------- -------------
                               AP        ACPII       ACMPII       AEPII          GN
------- ------------------ ----------- ----------- ------------ ----------- -------------
                                                                
(a)     Beneficial            -0-         -0-          -0-         -0-         31,737
        Ownership
------- ------------------ ----------- ----------- ------------ ----------- -------------
(b)     Percentage of        0.00%       0.00%        0.00%       0.00%        0.29%
        Class
------- ------------------ ----------- ----------- ------------ ----------- -------------
(c)     Sole Voting Power     -0-         -0-          -0-         -0-         31,737
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Shared Voting         -0-         -0-          -0-         -0-          -0-
        Power
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Sole Dispositive      -0-         -0-          -0-         -0-         31,737
        Power
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Shared                -0-         -0-          -0-         -0-          -0-
        Dispositive Power
------- ------------------ ----------- ----------- ------------ ----------- -------------
                               JD          GG          DJ           AM
------- ------------------ ----------- ----------- ------------ ----------- -------------
(a)     Beneficial           1,913       2,726        1,376       1,817
        Ownership
------- ------------------ ----------- ----------- ------------ ----------- -------------
(b)     Percentage of        0.02%       0.03%        0.01%       0.02%
        Class
------- ------------------ ----------- ----------- ------------ ----------- -------------
(c)     Sole Voting Power    1,913       2,726        1,376       1,817
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Shared Voting         -0-         -0-          -0-         -0-
        Power
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Sole Dispositive     1,913       2,726        1,376       1,817
        Power
------- ------------------ ----------- ----------- ------------ ----------- -------------
        Shared                -0-         -0-          -0-         -0-
        Dispositive Power
------- ------------------ ----------- ----------- ------------ ----------- -------------


Item 5.        Ownership of Five Percent or Less of a Class

Exit Filing --- See Attachment A

Item 6.        Ownership of More than Five Percent on Behalf of Another Person

Not applicable.

Item 7.        Identification   and   Classification  of  the  Subsidiary  Which
               Acquired the  Security  Being  Reported on By the Parent  Holding
               Company.

Not applicable.



                                                             Page 13 of 16 Pages


Item 8.        Identification and Classification of Members of the Group

No   reporting   person  is  a  member  of  a  group  as   defined   in  Section
240.13d-1(b)(1)(ii)(H) of the Act.

Item 9.        Notice of Dissolution of Group

Not applicable.

Item 10.       Certification

By signing below we certify  that, to the best of our knowledge and belief,  the
securities  referred to above were acquired and are held in the ordinary  course
of business  and were not  acquired  and are not held for the purpose of or with
the  effect  of  changing  or  influencing  the  control  of the  issuer  of the
securities  and were not  acquired and are not held in  connection  with or as a
participant in any transaction having that purpose or effect.

EXHIBITS

A:       Joint Filing Statement



                                                             Page 14 of 16 Pages

                                    Signature

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.


Date:    March 3, 2005



                                                  
ALTA PARTNERS                                        ALTA CALIFORNIA PARTNERS II, L.P.

                                                     By:  Alta California Management Partners II, LLC,
                                                                  Its General Partner

By:      /s/ Jean Deleage                            By:      /s/ Guy Nohra    
   -----------------------------------------            --------------------------------
         Jean Deleage, President                              Guy Nohra, Member


ALTA CALIFORNIA MANAGEMENT PARTNERS II, LLC          ALTA EMBARCADERO PARTNERS II, LLC



By:      /s/ Guy Nohra                               By:      /s/ Guy Nohra             
   -----------------------------------------            --------------------------------
         Guy Nohra, Member                                   Guy Nohra, Member


         /s/ Jean Deleage                                    /s/ Guy Nohra             
   -----------------------------------------            --------------------------------
         Jean Deleage                                           Guy Nohra


         /s/ Garrett Gruener                                 /s/ Alix Marduel   
   -----------------------------------------            --------------------------------
         Garrett Gruener                                      Alix Marduel


         /s/ Daniel Janney                                    
   -----------------------------------------  
         Daniel Janney




                                                             Page 15 of 16 Pages


                                    EXHIBIT A

                            AGREEMENT OF JOINT FILING


Date:    March 3, 2005


                                    Signature

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.




                                                  
ALTA PARTNERS                                        ALTA CALIFORNIA PARTNERS II, L.P.

                                                     By:  Alta California Management Partners II, LLC,
                                                                  Its General Partner

By:      /s/ Jean Deleage                            By:      /s/ Guy Nohra 
   -----------------------------------------            --------------------------------
         Jean Deleage, President                              Guy Nohra, Member


ALTA CALIFORNIA MANAGEMENT PARTNERS II, LLC          ALTA EMBARCADERO PARTNERS II, LLC



By:      /s/ Guy Nohra                               By:      /s/ Guy Nohra             
   -----------------------------------------            --------------------------------
         Guy Nohra, Member                                  Guy Nohra, Member


         /s/ Jean Deleage                                    /s/ Guy Nohra
   -----------------------------------------            --------------------------------
           Jean Deleage                                         Guy Nohra


         /s/ Garrett Gruener                                  /s/ Alix Marduel 
   -----------------------------------------            --------------------------------
         Garrett Gruener                                      Alix Marduel


         /s/ Daniel Janney                                    
   -----------------------------------------     
         Daniel Janney




                                  Attachment A

                                   EXIT FILING

Alta Partners provides  investment  advisory services to several venture capital
funds including Alta California Partners II, L.P. and Alta Embarcadero  Partners
II, LLC. On 2/22/05,  Alta  California  Partners  II, L.P.  distributed  987,524
shares of Common Stock and Alta Embarcadero  Partners II, LLC distributed 12,476
shares of Common  Stock.  The  respective  general  partners and members of Alta
California Partners II, L.P. and Alta Embarcadero Partners II, LLC exercise sole
voting and investment power in respect to the shares owned by such funds.

Certain  principals of Alta Partners are members of Alta  California  Management
Partners  II, LLC (which is a general  partner of Alta  California  Partners II,
L.P.) and  members of Alta  Embarcadero  Partners  II,  LLC.  As members of such
entities,  they may be deemed to share  voting and  investment  powers  over the
shares held by such funds. The principals of Alta Partners  disclaim  beneficial
ownership of all such shares held by the foregoing  funds,  except to the extent
of their proportionate pecuniary interests therein.

Mr. Guy Nohra,  Director, is a member of Alta California Management Partners II,
LLC (which is the general  partner of Alta  California  Partners II, L.P.) and a
member of Alta Embarcadero  Partners II, LLC. He disclaims  beneficial ownership
of all such  shares  held by the  foregoing  funds  except to the  extent of his
proportionate  pecuniary  interests  therein.  As a result of the 2/22/05  Stock
Distribution,  the Guy Paul and Linda Nohra,  Nohra Living Trust  received 1,737
shares of Common Stock, of which 1,626 shares were received from Alta California
Management  Partners II, LLC and 111 shares were received from Alta  Embarcadero
Partners II, LLC. He also holds Stock  Options for 30,000 shares of Common Stock
granted on 5/10/2004 that will vest one-third  annually over a three year period
and will expire on 5/10/2014.

Mr. Jean  Deleage is a member of Alta  California  Management  Partners  II, LLC
(which is the general partner of Alta California Partners II, L.P.) and a member
of Alta Embarcadero  Partners II, LLC. He disclaims  beneficial ownership of all
such  shares  held  by  the  foregoing   funds  except  to  the  extent  of  his
proportionate pecuniary interests therein.

As of February 22, 2005 - Common  Stock  Ownership:  Shares Owned  By/Affiliated
with Jean Deleage



 Beneficial Owner (issued in the name of)                  # of Shares         Date Acquired
 ----------------------------------------                  -----------         -------------
                                                                           
   Jean Deleage 1,913                                        (2)  2/22/05
   Deleage Children's Trust FBO Andre Deleage (1)            203  (3)            2/22/05
   Deleage Children's Trust FBO Emmanuel Deleage (1)         203  (3)            2/22/05
   Deleage Children's Trust FBO Philippe Deleage (1)         203  (3)            2/22/05
   Deleage Children's Trust FBO Michel Deleage (1)           203  (3)            2/22/05


(1)      Of which Mr.  Deleage,  a principal of Alta Partners (a venture capital
         firm) is neither a trustee nor claims beneficial ownership.
(2)      As a result of the 2/22/05 Stock  Distribution,  Mr.  Deleage  received
         1,913 shares of Common  Stock;  of which 813 shares were  received from
         Alta  California  Management  Partners  II, LLC and 1,100  shares  were
         received from Alta Embarcadero Partners II, LLC.

(3)      As a result of the  2/22/05  Stock  Distribution,  each of the  Deleage
         Children's  Trusts  received 203 shares of Common Stock Alta California
         Management Partners II, LLC.



Mr. Garrett Gruener is a member of Alta California  Management  Partners II, LLC
(which is the general partner of Alta California Partners II, L.P.) and a member
of Alta Embarcadero  Partners II, LLC. He disclaims  beneficial ownership of all
such  shares  held  by  the  foregoing   funds  except  to  the  extent  of  his
proportionate  pecuniary  interests  therein.  As a result of the 2/22/05  Stock
Distribution,  he received 2,726 shares of Common Stock.;  of which 1,626 shares
were received from Alta California  Management Partners II, LLC and 1,100 shares
were received from Alta Embarcadero Partners II, LLC.




Daniel Janney is a member of Alta California  Management Partners II, LLC (which
is the general  partner of Alta  California  Partners  II,  L.P.).  He disclaims
beneficial  ownership of all such shares held by the  foregoing  funds except to
the extent of his proportionate  pecuniary interests therein. As a result of the
2/22/05 Stock Distribution, the Daniel Janney and Noelle Montgomery Family Trust
received  1,376  shares of  Common  Stock  were  received  from Alta  California
Management Partners II, LLC.

Dr. Alix  Marduel is a member of Alta  California  Management  Partners  II, LLC
(which is the  general  partner  of Alta  California  Partners  II,  L.P.).  She
disclaims  beneficial  ownership of all such shares held by the foregoing  funds
except to the extent of her  proportionate  pecuniary  interests  therein.  As a
result of the 2/22/05 Stock Distribution,  the Lockard / Marduel Revocable Trust
received 1,817 shares of Common Stock;  of which 1,376 shares were received from
Alta  California  Management  Partners II, LLC and 441 shares were received from
Alta Embarcadero Partners II, LLC.

Alta Partners is a venture  capital firm with an office in San  Francisco.  Alta
Partners is  California  Corporation.  Alta  California  Partners  II, L.P. is a
Delaware  Limited  Partnership,  and  Alta  Embarcadero  Partners  II,  LLC is a
California Limited Liability Company.