UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE TO

Biosite Incorporated

Inca Acquisition, Inc.
Inverness Medical Innovations, Inc.

Transaction Valuation*		Amount of Filing Fee**
$1,603,420,070		$49,225.00

*		Estimated for purposes of calculating the filing fee only. This calculation assumes the purchase of 17,334,271 shares of the Common Stock of Biosite Incorporated at the tender offer price of $92.50 per share.
**		The amount of the filing fee, calculated in accordance with the Securities Exchange Act of 1934, as amended, equals $30.70 per million of transaction value.

þ		Check the box if any part of the fee is offset as provided by Rule 0-11(a)(2) and identify the filing with which the offsetting fee was previously paid. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.

Amount Previously Paid: $49,225.00		Filing Party: Inverness Medical Innovations, Inc.
Form or Registration No. Schedule TO		Date Filed: May 29, 2007

o		Check the box if the filing relates solely to preliminary communications made before the commencement of a tender offer.

          Check the appropriate boxes below to designate any transactions to which the statement relates:

þ      third-party tender offer subject to Rule 14d-1.

o      issuer tender offer subject to Rule 13e-4.

o      going-private transaction subject to Rule 13e-3.

o      amendment to Schedule 13D under Rule 13d-2.

     Check the following box if the filing is a final amendment reporting the results of the tender offer:    o

 

 

     This Amendment No. 6 (this “Amendment”) amends and supplements the Tender Offer Statement on Schedule TO (the “Schedule TO”) originally filed with the Securities and Exchange Commission (the “SEC”) on May 29, 2007, as amended by Amendment No. 1 on May 30, 2007, Amendment No. 2 on June 5, 2007, Amendment No. 3 on June 7, 2007, Amendment No. 4 on June 7, 2007 and Amendment No. 5 on June 12, 2007 relating to the offer by Inca Acquisition, Inc., a Delaware corporation (the “Purchaser”) and a wholly-owned subsidiary of Inverness Medical Innovations, Inc. (“Inverness”) to purchase all of the issued and outstanding shares of common stock, par value $0.01 per share, including the associated right to purchase series A participating preferred stock, par value $0.01 per share, (collectively, the “Shares”), of Biosite Incorporated, a Delaware corporation (“Biosite”), at a purchase price of $92.50 per share, plus, if the first time the Shares are accepted for payment (the “Acceptance Time”) shall not have occurred on or prior to July 2, 2007, an additional $0.015205 per Share for each day during the period commencing on July 3, 2007, through the Acceptance Time, less any applicable withholding taxes (the “Offer Price”), upon the terms and subject to the conditions set forth in the Offer to Purchase, dated May 29, 2007 (the “Offer to Purchase”), and in the related Letter of Transmittal (which, together with any amendments or supplements thereto, collectively constitute the “Offer”). Capitalized terms used and not otherwise defined in this Amendment shall have the meanings assigned to such terms in the Offer to Purchase or in the Schedule TO. This Amendment is being filed on behalf of Inverness and the Purchaser.

Subsequent Offering Period

     Item 11 of the Schedule TO, to the extent such Items incorporate by reference the information contained in the Offer, is hereby amended and supplemented as follows:

     The initial period of the Offer expired at 12:00 midnight, New York City time, on Monday, June 25, 2007. According to Computershare Trust Company, N.A., the depositary for the Offer, as of 12:00 midnight, New York City time, June 25, 2007, 16,051,933 Shares representing approximately 89.2% of all outstanding Shares were tendered pursuant to the Offer and not withdrawn, including 2,338,138 Shares representing 13.0% of all outstanding Shares which were tendered by notice of guaranteed delivery. The tendered Shares, together with the 750,000 Shares that Inverness currently owns, represent approximately 93.4% of all outstanding Shares. Purchaser has accepted all validly tendered Shares for payment pursuant to the terms of the Offer.

     On June 26, 2007, Inverness issued a press release announcing the results of the Offer and that Purchaser has commenced a subsequent offering period for all remaining untendered Shares expiring at 12:00 midnight, New York City time, on Thursday, June 28, 2007 (the end of the day on Thursday) unless further extended. During the subsequent offering period, holders of Shares who did not previously tender their Shares into the Offer may do so and will promptly receive the same $92.50 per Share cash consideration paid during the initial offering period. The procedures for accepting the Offer and tendering Shares during the subsequent offering period are the same as those described for the Offer in the Offer to Purchase except that (i) the guaranteed delivery procedures may not be used during the subsequent offering period and (ii) Shares tendered during the subsequent offering period may not be withdrawn. The full text of the press release issued by Inverness is attached hereto as Exhibit (a)(5)(H) and is incorporated herein by reference.

Miscellaneous

Item 12 of the Schedule TO is hereby amended and supplemented to include the following:           “(a)(5)(H) Press Release issued by Inverness Medical Innovations, Inc. on June 26, 2007.”

SIGNATURES

     After due inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

INCA ACQUISITION, INC.

By:		/s/ Jay McNamara
Name:		Jay McNamara
Title:		Assistant Secretary

INVERNESS MEDICAL INNOVATIONS, INC.

By:		/s/ Jay McNamara
Name:		Jay McNamara
Title:		Senior Counsel – Corporate and Finance

Date: June 26, 2007

INDEX TO EXHIBITS

(a)(1)(A)		Offer to Purchase, dated as of May 29, 2007.*
(a)(1)(B)		Letter of Transmittal.*
(a)(1)(C)		Notice of Guaranteed Delivery.*
(a)(1)(D)		Letter to Brokers, Dealers, Banks, Trust Companies and other Nominees.*
(a)(1)(E)		Letter to Clients for use by Brokers, Dealers, Banks, Trust Companies and other Nominees.*
(a)(1)(F)		Guidelines for Certification of Taxpayer Identification Number on Substitute Form W-9.*
(a)(1)(G)		Summary Advertisement published on May 29, 2007.*
(a)(5)(A)		Press Release issued by Inverness Medical Innovations, Inc. on May 9, 2007 (incorporated by reference to the Schedule TO-C filed by Inverness Medical Innovations, Inc. on May 9, 2007).*
(a)(5)(B)		Press Release issued by Inverness Medical Innovations, Inc. on May 11, 2007 (incorporated by reference to the Schedule TO-C filed by Inverness Medical Innovations, Inc. on May 11, 2007).*
(a)(5)(C)		Joint press release issued by Inverness Medical Innovations, Inc. and Biosite Incorporated, dated May 17, 2007 (incorporated by reference to the Schedule TO-C filed by Inverness Medical Innovations, Inc. on May 18, 2007).*
(a)(5)(D)		Press Release issued by Inverness Medical Innovations, Inc. on May 29, 2007.*
(a)(5)(E)		Presentation given to Biosite employees on May 30, 2007. *
(a)(5)(F)		Press Release issued by Inverness Medical Innovations, Inc. on June 7, 2007.*
(a)(5)(G)		Investor presentation dated June 12, 2007.*
(a)(5)(H)		Press Release issued by Inverness Medical Innovations, Inc. on June 26, 2007.
(b)(1)		Commitment Letter dated May 14, 2007, by and among General Electric Capital Corporation, UBS Loan Finance LLC and Inverness Medical Innovations, Inc. (incorporated by reference to Exhibit 99.2 to the Current Report on Form 8-K filed by Inverness Medical Innovations, Inc. on May 15, 2007) (superceded in its entirety by Exhibit (b)(3)).*
(b)(2)		Commitment Letter dated May 14, 2007, by and among UBS Loan Finance LLC, UBS Securities LLC, General Electric Capital Corporation and Inverness Medical Innovations, Inc. (incorporated by reference to Exhibit 99.3 to the Current Report on Form 8-K filed by Inverness Medical Innovations, Inc. on May 15, 2007) (superceded in its entirety by Exhibit (b)(3)).*
(b)(3)		Commitment Letter dated June 5, 2007, by and among UBS Loan Finance LLC and General Electric Capital Corporation and Inverness Medical Innovations, Inc.*
(d)(1)		Agreement and Plan of Merger, dated as of May 17, 2007, by and among Inverness Medical Innovations, Inc., the Purchaser and Biosite Incorporated (incorporated by reference to Exhibit 2.1 to the Current Report on Form 8-K filed by Inverness Medical Innovations, Inc. on May 18, 2007).*