SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                          ----------------------------

                                    FORM 8-K

                                 CURRENT REPORT
                       PURSUANT TO SECTION 13 OR 15 (d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934


      Date of Report (Date of earliest event reported): September 25, 2006

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                             SIGA TECHNOLOGIES, INC.
             (Exact name of registrant as specified in its charter)


           DELAWARE                       0-23047                13-3864870
(State or other jurisdiction of   (Commission file number)    (I.R.S. employer
incorporation or organization)                               identification no.)


420 LEXINGTON AVENUE, SUITE 408
      NEW YORK, NEW YORK                                                10170
    (Address of principal                                             (Zip code)
      executive offices)

       Registrant's telephone number, including area code: (212) 672-9100


Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

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     Written communications pursuant to Rule 425 under the Securities Act (17
CFR 230.425)

     [X] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
CFR 240.14a-12)

     Pre-commencement communications pursuant to Rule 14d-2(b) under the
Exchange Act (17 CFR 240.14d-2(b))

     Pre-commencement communications pursuant to Rule 13e-4(c) under the
Exchange Act (17 CFR 240.13e-4(c))




ITEM 8.01. OTHER EVENTS.

On September 25, 2006, PharmAthene, Inc., a Delaware corporation ("PharmAthene"
or the "Company"), issued a press release pursuant to which it announced that it
has been awarded a multi-year contract valued at up to $213 million from the
Department of Defense U.S. Army Space and Missile Command, for advanced
development of the Company's broad spectrum chemical nerve agent prophylaxis,
Protexia(R). Protexia is a form of recombinant human butyrylcholinesterase
(rBChE), a potent organophosphorus (OP) scavenger protein, being developed for
use as a prophylactic to protect U.S. military personnel and civilians from the
toxic effects of chemical nerve agents. A copy of the press release is attached
hereto as Exhibit 99.1, which is incorporated by reference in this Item 8.01.

Under the contract, PharmAthene will be responsible for the conduct and
oversight of all product development activities. The initial stage of
development, for which $34.7 million has been allocated, includes manufacturing
process development, preclinical safety and toxicity testing, submission of an
Investigational New Drug (IND) Application with the United States Food and Drug
Administration (FDA), and initiation of a Phase I clinical trial. Following the
successful completion of the Phase I clinical trial, the government may exercise
its option to fund additional development activities beyond the initial $34.7
million, leading to FDA licensure. The contract also provides the Department of
Defense with the option to procure an initial 90,000 doses of Protexia.



ITEM 9.01.  FINANCIAL STATEMENTS AND EXHIBITS.

(c)  Exhibits

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Exhibit No.      Description
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99.1             Press Release dated September 25, 2006.
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                                    SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                      SIGA TECHNOLOGIES, INC.


                                      By: /s/ Thomas N. Konatich
                                          ----------------------
                                          Name: Thomas N. Konatich
                                          Title: Acting Chief Executive Officer
                                                 & Chief Financial Officer


Date: September 25, 2006