UNITED STATES                        ----------------------------------
     WASHINGTON, D.C. 20549
                                              OMB Number:
          FORM 12b-25                         Expires:
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                                              hours per response

                                                    CUSIP NUMBER


(Check One):  [x] Form 10-K  [ ] Form 20-F  [ ] Form 11-K
              [ ] Form 10-Q  [ ] Form N-SAR

                     For the Period Ended: January 31, 2002

[  ] Transition Report on Form 10-K
[  ] Transition Report on Form 20-F
[  ] Transition Report on Form 11-K
[  ] Transition Report on Form 10-Q
[  ] Transition Report on Form N-SAR

                For the Transition Period Ended:_________________

          Read Instruction Before Preparing Form. Please Print or Type.

         Nothing in this form shall be construed to imply that the Commission
has verified any information contained herein.

         If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:


                         PART I - REGISTRANT INFORMATION

Full Name of Registrant:  BioSpecifics Technologies Corp.

Former Name if Applicable:  N/A

Address of Principal Executive Office (Street and number):  35 Wilbur Street

City, State and Zip Code:  Lynbrook, New York  11563

                        PART II - RULES 12b-25(b) AND (c)

         If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rule 12b-25(b), the
following should be completed. (Check box if appropriate)

     | (a)     The reasons described in reasonable detail in Part III of this
     |         form could not be eliminated without unreasonable effort or
     |         expense;
     | (b)     The subject annual report, semi-annual report, transition report
     |         on Form 10-K, Form 20-F, 11-K or Form N-SAR, or portion thereof,
     |         will be filed on or before the fifteenth calendar day following
[X}  |         the prescribed due date; or the subject quarterly report of
     |         transition report on Form 10-Q, or portion thereof will be filed
     |         on or before the fifth calendar day following the prescribed due
     |         date; and
     | (c)     The accountant's statement or other exhibit required by Rule
     |         12b-25(c) has been attached if applicable.

                              PART III - NARRATIVE

         State below in reasonable detail the reasons why Forms 10-K, 20-F,
11-K, 10-Q, N-SAR, or the transition report or portion thereof, could not be
filed within the prescribed time period. (Attach extra sheets if needed.)

         The Company's Annual Report on Form 10-KSB will not be filed within the
prescribed time period because of unexpected delays in the preparation of
the 10-KSB.

                           PART IV - OTHER INFORMATION

         Name and telephone number of person to contact in regard to this

          Albert Horcher             516                     593-7000
          --------------         -----------              -----------------
            (Name)               (Area Code)             (Telephone Number)

(1)      Have all other periodic reports required under Section 13 or 15(d) of
         the Securities Exchange Act of 1934 or Section 30 of the Investment
         Company Act of 1940 during the preceding 12 months or for such shorter
         period that the registrant was required to file such report(s) been
         filed? If answer is no, identify report(s).
                                                           [X] Yes      [ ] No

(2)      Is it anticipated that any significant change in results of operations
         from the corresponding period for the last fiscal year will be
         reflected by the earnings statements to be included in the subject
         report or portion thereof?
                                                           [ ] Yes       [X] No

        If so, attach an explanation of the anticipated change, both
         narratively and quantitatively, and, if appropriate, state the reasons
         why a reasonable estimate of the results cannot be made.


                         BioSpecifics Technologies Corp.
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.

Date:  April 29, 2002               By:  /s/ Albert Horcher
       -----------------                -----------------------------------
                                        Name: Albert Horcher
                                        Title:  Secretary, Treasurer, Principal
                                        Financial and Chief Accounting Officer

         Instruction: The form may be signed by an executive officer of the
registrant or by any other duly authorized representative. The name and title of
the person signing the form shall be typed or printed beneath the signature. If
the statement is signed on behalf of the registrant by an authorized
representative (other than an executive officer), evidence of the
representative's authority to sign on behalf of the registrant shall be filed
with the form.


         Intentional misstatements or omissions of fact constitute Federal
Criminal Violations (See 18 U.S.C. ss. 1001).

                              GENERAL INSTRUCTIONS

1.       This form is required by Rule 12b-25 (17 C.F.R.ss. 240.12b-25) of the
         General Rules and Regulations under the Securities Exchange Act of

2.       One signed original and four conformed copies of this form and
         amendments thereto must be completed and filed with the Securities and
         Exchange Commission, Washington, D.C. 20549, in accordance with Rule
         0-3 of the General Rules and Regulations under the Act. The information
         contained in or filed with the form will be made a matter of public
         record in the Commission files.

3.       A manually signed copy of the form and amendments thereto shall be
         filed with each national securities exchange on which any class of
         securities of the registrant is registered.

4.       Amendments to the notifications must be filed on form 12b-25 but need
         not restate information that has been correctly furnished. The form
         shall be clearly identified as an amended notification.

5.       Electronic Filers. This form shall not be used by electronic filers
         unable to timely file a report solely due to electronic difficulties.
         Filers unable to submit a report within the time period prescribed due
         to difficulties in electronic filing should comply with either Rule 201
         or Rule 202 of Regulation S-T (ss.ss. 232.201 or ss.ss. 232.202 of this
         chapter) or apply for an adjustment in filing date pursuant to Rule
         13(b) of Regulation S-T (ss.ss. 232.13(b) of this chapter).